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Table 4 INR response after the first dose of PCC3 or LDrFVIIa

From: Comparison of 3-Factor Prothrombin Complex Concentrate and Low-Dose Recombinant Factor VIIa for Warfarin Reversal

 

PCC3 (n = 74)

LD rFVIIa (n = 32)

p

INR baseline*:

3.1 [2.3-4.1]

2.8 [2.2-3.6]

0.52

INR post coagulation factor*:

1.75 [1.5-2.0]

1.25 [1.0-1.25]

<0.05

INR Δ*:

1.2 [0.7-2.2]

1.5 [1.2-2.0]

0.14

% Δ INR*:

38.8% [30.7%-56.0%]

54.1% [47.3%-62.7%]

0.002

n (%) ≤ 1.5:

25 (33.8%)

23 (71.9%)

0.001

Time (h:mm)*:

3:53 [2:32-7:17]

4:30 [2:21-6:25]

0.78

  1. *Data as median [IQR].
  2. PCC3, 3 factor Prothrombin Complex Concentrate; LDrFVIIa, low dose recombinant factor VII activated; INR, International Normalized Ratio.
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World Journal of Emergency Surgery

ISSN: 1749-7922