Table 2 Hypertonic saline after a damage control laparotomy. Randomized controlled clinical trial. Outcomes

Abdominal closure in the first 7 days, n (%)

17/24 (70.8%)

19/24 (79.2%)

0.71¹

Day 28 mortality, n (%)

3/26 (11.5%)

2/24 (8.0%)

1.00²

Abdominal compartment syndrome, n (%)

0 (–)

2 (8.0%)

0.27²

Total SOFA score

5 (7.5–9)

6 (4–14)

0.95³

Number of subjects with SOFA score > 6, n (%)

13 (59.1%)

12 (48.0%)

0.32¹

ICU-free days in the first 30 days, median (IQR)

16 (1–23)

19 (11–24)

0.57³

Fluid balance

 Day 1, c.c., median (IQR)

2165 (1180–4119)

1828 (427–3344)

0.21³

 Day 2, c.c., median (IQR)

678 (106–1599)

387 (− 125–1165)

0.58³

 Day 3, c.c., median (IQR)

261 (− 32–950)

170 (− 136–580)

0.43³

 First 72 h, c.c., median (IQR)

3957 (1767–5946)

2486 (650–5578)

0.29³