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Table 2 Results of a clinical double-blind trial about the use of antibiotics in severe acute pancreatitis [21]

From: Questions about the use of antibiotics in acute pancreatitis

 

Intention to treat (114 patients)

Pancreatic necrosis (CT) (76 patients)

Treatment

Ciprofloxacin/Metronidazole (58 patients)

Placebo (56 patients)

Ciprofloxacin/Metronidazole (58 patients)

Placebo (56 patients)

Mortality

5%

7%

7%

11%

Surgical treatment

17%

11%

24%

19%

Necrosis infection

12%

9%

17%

14%

Protocol opened

28%*

46%

37%

57%