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Table 4 Predictors of mortality according to univariate and multivariate logistic regression analysis

From: Clinical profile and outcome of surgical treatment of perforated peptic ulcers in Northwestern Tanzania: A tertiary hospital experience

Predictor (independent) variable Survivors N (%) Non-survivors n (%) Univariate analysis Multivariate analysis
    O.R. (95% C.I.) p-value (O.R. 95% C.I.) p-value
Age       
< 40 51(98.1) 1 (1.9)     
≥40 24(75.0) 8 (25.0) 2.33(1.25-3.42) 0.032 4.61(2.72-7.91) 0.002
Sex       
Male 42 (87.5) 6 (12.5)     
Female 33 (91.7) 3 (8.3) 1.25 (0.32-3.56) 0.896 2.93 (0.94-3.81) 0.983
Premorbid illness       
Yes 2 (33.3) 4 (66.7)     
No 73 (93.6 5 (6.4) 6.21(1.49-7.01) 0.039 3.78(2.98-7.90) 0.017
Previous PUD       
Yes 23 (88.0) 3(12.0)     
No 52 (89.7) 6 (10.3) 1.75(0.76-4.34) 0.896 3.11(0.98-4.88) 0.345
HIV status       
Positive 1(12.5) 7 (87.5)     
Negative 74(97.4) 2 (2.6) 0.56(0.12-0.86) 0.005 1.74(1.21-4.98) 0.001
CD 4+ count       
< 200 cells/μl 1(50.0) 1 (50.0)     
≥ 200 cells/μl 4(66.7) 2 (33.3) 5.91(2.76-7.99) 0.001 1.65(1,22-7.43) 0.000
Duration of illness       
<24 hours 23 (92.0) 2 (8.0)     
≥24 hours 48 (87.3) 7 (12.7) 2.32(0.54-6.45) 0.986 0.09(0.02-1.11) 0.315
Shock on admission (SBP < 90 mmHg)       
Yes 28 (77.8) 8 (22.2)     
No 47 (87.9) 1(2.1) 7.9(3.98-9.88) 0.022 3,74(2,11-7.76) 0.005
Timing of surgical treatment       
< 48 hours 19 (95.0) 1 (5.0)     
≥ 48 hours 56 (87.5) 8 (12.5%) 2.87(2.11-7.21) 0.044 2.91(1.22-6.66) 0.028
Amount of fluid (mls       
< 200 19 (95.0) 1 (5.0)     
≥200 56(87.5) 8 (12.5) 0.67(0.23-4.65) 0.982 1.61(0.89-2.73) 0.067
Site of perforation       
Duodenum 72 (93.4) 5 (6.6)     
Gastric 2 (33.3) 4 (66.7) 5.81(3.33-6.92) 0.012 1.35(1.11-3.86) 0.018
Size of ulcer       
Sealed 7 (100.0) 0(0)     
<5 mm 12 (92.3) 1(7.7)     
≥5 mm 56 (87.5) 8(12.5) 1.98(0.45-3.82) 0.987 3.13(0.99-4.89) 0.453
Complications       
Present 18 (72.0) 7(28.0)     
Absent 57(96.6) 2 (3.4) 1.98(1.54-7.93) 0.005 2.86(2.22-6.45) 0.011