Table 1 Demographics & Baseline Characteristics
From: The utility of recombinant factor VIIa as a last resort in trauma
Variable | Last resort (n=11) | Non-last resort (n=60) | P Value |
|---|---|---|---|
Age (years) | 27 (22, 39) | 35 (24, 48) | 0.14 |
Male (%) | 82 | 63 | 0.3 |
Penetrating (%) | 45 | 28 | 0.2 |
ISS | 47 (±16) | 43(±15) | 0.4 |
Head AIS | 0 (0, 2) | 2 (0, 5) | 0.1 |
Platelets | 76 (±57) | 184 (±95) | <0.01 |
Fibrinogen | 0.64 (±0.3) | 0.9 (±0.5) | 0.07 |
INR | 2.1 (1.8,2.7) | 1.4(1.2, 1.6) | 0.03 |
Hemoglobin | 83 (±17) | 100 (±28) | 0.02 |
pH | 6.87 (±0.11) | 7.26 (±0.11) | <0.01 |
Rate of Bleeding (RBC/hr) | 4 (±1.5) | 3 (±1.7) | 0.03 |
Time to rFVIIa (hr) | 3.7 (±2.2) | 6.2 (4.5) | 0.04 |
rFVIIa Dose (ug/Kg) | 89 (±43) | 116 (±79) | 0.14 |
> 1 rFVIIa doses (%) | 9 | 33 | 0.05 |