Table 2 Characteristics of the randomized controlled trials on IAP, IAH, and ACS
Author | N | Study population | Intervention | Control | Main conclusion |
|---|---|---|---|---|---|
Celik[15] | 100 | Patients undergoing elective | 5 different IAP levels; 8, 10, | NA | No effect of IAP levels on gastric |
| Â | Â | Laparoscopic cholecystectomy | 12, 14, and 16Â mm Hg | Â | intramucosal pH |
Basgul[16] | 22 | Patients undergoing elective laparoscopic cholecystectomy | Low IAP level (10Â mm Hg) | High IAP level (14Y15 mm Hg) | Less depression of immune function (expressed as interleukin 2 and 6) in the low IAP group |
O’Mara[17] | 31 | Burn patients (>25% TBS with inhalation injury or >40% TBS without) | Plasma resuscitation | Crystalloid resuscitation | Less increase in IAP and less volume requirement in plasma-resuscitated patients |
Sun[18] | 110 | Severe acute pancreatitis patients | Routine conservative treatment combined with indwelling catheter drainage | Routine conservative treatment | Lower mortality, lower APACHE II scores after 5 d and shorter hospitalization times in intervention group |
Bee[19] | 51 | Patients undergoing emergency laparotomy requiring temporary abdominal closure | Vacuum-assisted closure | Mesh closure | No signification differences in delayed fascial closure or fistula rate |
Karagulle[20] | 45 | Patients undergoing elective laparoscopic cholecystectomy | 3 different IAP levels; 8, 12, and 15Â mm Hg | NA | Similar effects on pulmonary function test results |
Zhang[21] | 80 | Severe acute pancreatitis patients | Da-Cheng-Qi decoction enema and sodium sulphate orally | Normal saline enema | Lower IAP levels in intervention group |
Ekici[22] | 52 | Patients undergoing elective laparoscopic cholecystectomy | Low IAP level (7Â mm Hg) | High IAP level (15Â mm Hg) | More pronounced effect of high IAP on QT dispersion |
Joshipura[23] | 26 | Patients undergoing elective laparoscopic cholecystectomy | Low IAP level (8Â mm Hg) | High IAP level (12Â mm Hg) | Decrease in postoperative pain and hospital stay, and preservation of lung function in low pressure level group |
Mao[24] | 76 | Severe acute pancreatitis patients | Controlled fluid resuscitation | Rapid fluid resuscitation | Lower incidence of ACS in controlled fluid resuscitation group (i.a.) |
Yang[25] | 120 | Severe acute pancreatitis patients | Colloid plus crystalloid resuscitation | Crystalloid resuscitation | Decline of IAP was significant higher in crystalloid plus colloid group |
Celik[26] | 60 | Patients undergoing elective laparoscopic cholecystectomy | 3 different IAP levels; 8, 12 and 14Â mm Hg | NA | No effect of IAP level on postoperative pain |
Chen[27] | 60 | ICU patients with multiorgan failure | Tongfu Granule | Placebo | Decreased IAP in intervention group |
| Â | Â | Â | (Traditional Chinese medicines) | Â | |
Agarwal[28] | 190 | Patients undergoing emergency laparotomy | Reinforced tension line sutures | Continuous suturing | No difference in IAP but increased incidence of fascial dehiscence in continuous suture group |
Du[29] | 41 | Severe acute pancreatitis patients | Hydroxyethyl starch resuscitation | Ringer’s lactate resuscitation | Lower incidence of IAH and reduced use of mechanical ventilation in intervention group |
Topal[30] | 60 | Patients undergoing elective laparoscopic cholecystectomy | 3 different IAP levels; 10, 13, and 16Â mm Hg | NA | No differences on thromboelastography |