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Table 2 Characteristics of the randomized controlled trials on IAP, IAH, and ACS

From: Successful interventional management of abdominal compartment syndrome caused by blunt liver injury with hemorrhagic diathesis

Author

N

Study population

Intervention

Control

Main conclusion

Celik[15]

100

Patients undergoing elective

5 different IAP levels; 8, 10,

NA

No effect of IAP levels on gastric

  

Laparoscopic cholecystectomy

12, 14, and 16 mm Hg

 

intramucosal pH

Basgul[16]

22

Patients undergoing elective laparoscopic cholecystectomy

Low IAP level (10 mm Hg)

High IAP level (14Y15 mm Hg)

Less depression of immune function (expressed as interleukin 2 and 6) in the low IAP group

O’Mara[17]

31

Burn patients (>25% TBS with inhalation injury or >40% TBS without)

Plasma resuscitation

Crystalloid resuscitation

Less increase in IAP and less volume requirement in plasma-resuscitated patients

Sun[18]

110

Severe acute pancreatitis patients

Routine conservative treatment combined with indwelling catheter drainage

Routine conservative treatment

Lower mortality, lower APACHE II scores after 5 d and shorter hospitalization times in intervention group

Bee[19]

51

Patients undergoing emergency laparotomy requiring temporary abdominal closure

Vacuum-assisted closure

Mesh closure

No signification differences in delayed fascial closure or fistula rate

Karagulle[20]

45

Patients undergoing elective laparoscopic cholecystectomy

3 different IAP levels; 8, 12, and 15 mm Hg

NA

Similar effects on pulmonary function test results

Zhang[21]

80

Severe acute pancreatitis patients

Da-Cheng-Qi decoction enema and sodium sulphate orally

Normal saline enema

Lower IAP levels in intervention group

Ekici[22]

52

Patients undergoing elective laparoscopic cholecystectomy

Low IAP level (7 mm Hg)

High IAP level (15 mm Hg)

More pronounced effect of high IAP on QT dispersion

Joshipura[23]

26

Patients undergoing elective laparoscopic cholecystectomy

Low IAP level (8 mm Hg)

High IAP level (12 mm Hg)

Decrease in postoperative pain and hospital stay, and preservation of lung function in low pressure level group

Mao[24]

76

Severe acute pancreatitis patients

Controlled fluid resuscitation

Rapid fluid resuscitation

Lower incidence of ACS in controlled fluid resuscitation group (i.a.)

Yang[25]

120

Severe acute pancreatitis patients

Colloid plus crystalloid resuscitation

Crystalloid resuscitation

Decline of IAP was significant higher in crystalloid plus colloid group

Celik[26]

60

Patients undergoing elective laparoscopic cholecystectomy

3 different IAP levels; 8, 12 and 14 mm Hg

NA

No effect of IAP level on postoperative pain

Chen[27]

60

ICU patients with multiorgan failure

Tongfu Granule

Placebo

Decreased IAP in intervention group

   

(Traditional Chinese medicines)

 

Agarwal[28]

190

Patients undergoing emergency laparotomy

Reinforced tension line sutures

Continuous suturing

No difference in IAP but increased incidence of fascial dehiscence in continuous suture group

Du[29]

41

Severe acute pancreatitis patients

Hydroxyethyl starch resuscitation

Ringer’s lactate resuscitation

Lower incidence of IAH and reduced use of mechanical ventilation in intervention group

Topal[30]

60

Patients undergoing elective laparoscopic cholecystectomy

3 different IAP levels; 10, 13, and 16 mm Hg

NA

No differences on thromboelastography

  1. N: number of patients, APACHE: Acute Physiology And Chronic Health Evaluation, NA: not applicable/available; TBS: Total body surface area, IAP: intra-abdominal pressure, IAH: intra-abdominal hypertension, ACS: abdominal compartment syndrome.