Table 2 Indication for warfarin anticoagulation reversal
Characteristics | PCC3 (n = 74) | LD rFVIIa (n = 32) | p |
|---|---|---|---|
Neuro, n* | 39 | 23 | 0.07 |
CH | 19 | 9 | 0.79 |
SDH | 7 | 9 | 0.014 |
SAH | 6 | 2 | 1.00 |
SCI | 1 | 2 | 0.22 |
TBI | 6 | 1 | 0.67 |
Craniotomy | 0 | 1 | 0.30 |
Abdominal | 11 | 3 | 0.55 |
Intraperitoneal Hem. | 2 | 0 | 1.00 |
Retroper. hematoma | 1 | 0 | 1.00 |
GIB | 2 | 1 | 1.00 |
Perf. Viscous/ | 0 | 1 | 0.30 |
peritonitis | |||
Pneumoperitoneum | 1 | 0 | 1.00 |
Incarcerated hernia | 2 | 1 | 1.00 |
Acute abdomen | 1 | 0 | 1.00 |
Diverticulitis | 1 | 0 | 1.00 |
Colonic perforation | 1 | 0 | 1.00 |
Other | 25 | 8 | 0.37 |
Orthopedic | 2 | 3 | 0.16 |
Fall w/external inj. | 0 | 1 | 0.30 |
Multiple trauma | 0 | 1 | 0.30 |
Pulmonary contusion | 1 | 0 | 1.00 |
Chest wall trauma | 1 | 0 | 1.00 |
Pacemaker placement | 2 | 0 | 1.00 |
Emergent surgery | 4 | 1 | 1.00 |
Ruptured iliac | 1 | 0 | 1.00 |
Artery aneurysm | |||
Pseudoaneurysm | 1 | 0 | 1.00 |
CFA | |||
Hematoma | 3 | 0 | 1.00 |
Pneumothorax | 2 | 0 | 1.00 |
Posthemorrhagic | 1 | 0 | 1.00 |
Hydrocephalus | |||
Epistaxis | 0 | 1 | 0.30 |
INR > 8 | 6 | 0 | 0.18 |
Unknown | 1 | 0 | 1.00 |