PCC3 (n = 74) | LD rFVIIa (n = 32) | p | |
---|---|---|---|
Initial coagulation factor dose | |||
Total Dose (units)* | 1540 [1429-1978] | 1000 [1000-1000] | NA |
Weight-based Dose (units/kg)* | 19.9 [18.6-20.8] | 11.5 [10.1-15.0] | NA |
Other reversal agents administered | |||
Vit K, n (%) | 57 (77.0%) | 22 (68.8%) | 0.37 |
FFP, n (%) | 49 (66.2%) | 21 (65.6%) | 0.95 |
FFP units* | 2 [0-4] | 2 [0-4] | 0.75 |
Total cost for reversal agents: | |||
Coagulation factor (USD)*: | 1116.50 [963-1718] | 1230 [1170-1360] | 0.26 |
FFP(USD)*: | 393 [0-496] | 393 [0-496] | 0.65 |
Total(USD)*: | 1526 [1299-2047] | 1609.50 [1360-1756] | <0.05 |