Table 3 Demographic and clinical characteristics of patients stratified by clinical outcome
Characteristic | Clinical success group (n = 194) | Clinical failure group (n = 66) | P value |
|---|---|---|---|
Mean ± SD age, years | 46.4 ± 19 | 56.2 ± 21 | <0.05 |
Males, n (%) | 113 (58.2) | 36 (54.5) | NS |
Comorbidities, n (%) | |||
Diabetes mellitus | 7 (3.6) | 5 (7.5) | NS |
Obesity | 9 (4.6) | 3 (4.5) | NS |
Lifestyle factors, n (%) | |||
Smoking | 22 (11.3) | 5 (7.5) | NS |
Alcoholism | 0 (0) | 0 (0) | NS |
Therapeutic failure risk factors, n (%) | |||
Age > 65 years | 38 (19.5) | 25 (37.8) | <0.05 |
Cancer | 8 (4.1) | 8 (12.1) | <0.05 |
Anemia | 6 (3.1) | 10 (15.2) | <0.05 |
Liver cirrhosis | 1 (0.5) | 0 (0) | NS |
Renal failure | 1 (0.5) | 1 (1.5) | NS |
End stage renal failure | 2 (1.0) | 0 (0) | NS |
Coagulopathy | 2 (1.0) | 0 (0) | NS |
Immunosuppression | 1 (0.5) | 1 (1.5) | NS |
Primary surgical intervention site, n (%) | |||
Appendix | 132 (68.0) | 30 (45.4) | <0.05 |
Lower GI tract | 23 (11.8) | 28 (42.4) | <0.05 |
Upper GI tract | 10 (5.1) | 3 (4.5) | NS |
Gall-bladder | 13 (6.7) | 1 (1.5) | NS |
Peritoneal abscess | 13 (6.7) | 3 (4.5) | NS |
Other | 3 (1.5) | 1 (1.5) | NS |
Surgical approach, n (%) | |||
Laparoscopy | 111 (57.2) | 24 (36.3) | <0.05 |
Laparotomy | 76 (39.2) | 40 (60.6) | <0.05 |
Percutaneous | 7 (3.6) | 2 (3.0) | NS |
Antibiotic treatment, n (%) | |||
Monotherapy | 101 (52.1) | 46 (69.7) | <0.05 |
Combination therapy | 93 (47.9) | 20 (30.3) | <0.05 |
Illness severity markers, n (%) | |||
Parenteral nutrition | 27 (13.9) | 25 (37.8) | <0.05 |
Central venous catheter | 16 (8.2) | 24 (36.3) | <0.05 |
Antifungal drugs | 12 (6.2) | 16 (24.2) | <0.05 |
Enteral nutrition | 10 (5.2) | 12 (18.2) | <0.05 |
Invasive mechanical ventilation | 6 (3.1) | 14 (21.2) | <0.05 |
ICU admission, n (%) | 6 (3.1) | 18 (27.3) | <0.05 |
Mortality rate, n (%) | 0 (0) | 6 (9.1) | NS |