Skip to main content

Table 1 Characteristics of eligible studies

From: A systematic review and meta-analysis of randomised controlled trials of delayed primary wound closure in contaminated abdominal wounds

Study Diseases Age group Incision Prophylaxis antibiotics Follow up time   Intervention
Pettigrew 1981[24] Perforated and gangrenous appendicitis Adults and children Abdominal right lower quadrant (grid iron) and paramedian No 4 weeks PC (n = 80) Interrupted nylon sutures (with topical ampicillin in group B (n = 39)
DPC (n =42) Dressing changed was not specified. Wound was closed by interrupted nylon sutures on postoperative day 5
Tsang 1992[23] Perforated and gangrenous appendicitis Children Abdominal right lower quadrant Yes Not stated PC (n = 38) Interrupted nylon sutures
DPC (n = 25) Saline dressing daily until day 4 then closed the wound with Steri-Strip
Cohn 2001[26] Perforated appendicitis, other perforated viscus, traumatic injuries more than 4 hours old, or intra-abdominal abscesses Adults Abdominal right lower quadrant and midline Not stated 1 month PC (n =23) Wound were closed with skin staples
DPC (n =26) Wound packed with saline-soaked gauze, evaluated 3 days after surgery for closure with adhesive strip the next day if appropriate
Chatwiriya-charoen 2002[25] Perforated appendicitis Children Abdominal right lower quadrant Yes 5-14 days after discharge PC (n =22) Not stated
DPC (n =22) Dressing daily and packed with Betadine gauze 5–10 days until suitable for suture
Lahat 2005[17] Ileostomy closure Adults Ileostomy wound Yes 2 weeks PC (n =20) Skin was closed with skin staples
DPC (n =20) Wound packed with saline-soaked gauze and were not manipulated until day 3 for evaluation and closure on day 4 with nylon sutures if appropriate
Duttaroy 2009[7] Peptic perforations, typhoid perforations, appendicular perforation/abscesses, penetrating or blunt abdominal injuries with gastrointestinal perforation, or intraperitoneal abscesses Adults and children Abdominal Yes 4 weeks PC (n =40) Interrupted 2–0 polyamide sutures
DPC (n =37) Packed with saline-soaked gauze for 48 hours then the wound was evaluated for suturing next day with interrupted 2–0 polyamide sutures
Chiang 2012[16] Perforated appendicitis Adults and children Right lower quadrant Yes Not stated PC (n =36) Interrupted nylon sutures
DPC (n =34) Packed with Betadine-soaked gauze and changed daily until day 5 or later for DPC
Khan 2012[18] Complicated appendicitis (grossly inflamed, gangrenous, or perforated appendicitis) Adults Right lower quadrant Yes Not stated PC (n =50) Not stated
       DPC (n =50) Daily or twice dressing until postoperative day 3-5