Skip to main content

Table 1 Characteristics of eligible studies

From: A systematic review and meta-analysis of randomised controlled trials of delayed primary wound closure in contaminated abdominal wounds

Study

Diseases

Age group

Incision

Prophylaxis antibiotics

Follow up time

 

Intervention

Pettigrew 1981[24]

Perforated and gangrenous appendicitis

Adults and children

Abdominal right lower quadrant (grid iron) and paramedian

No

4 weeks

PC (n = 80)

Interrupted nylon sutures (with topical ampicillin in group B (n = 39)

DPC (n =42)

Dressing changed was not specified. Wound was closed by interrupted nylon sutures on postoperative day 5

Tsang 1992[23]

Perforated and gangrenous appendicitis

Children

Abdominal right lower quadrant

Yes

Not stated

PC (n = 38)

Interrupted nylon sutures

DPC (n = 25)

Saline dressing daily until day 4 then closed the wound with Steri-Strip

Cohn 2001[26]

Perforated appendicitis, other perforated viscus, traumatic injuries more than 4 hours old, or intra-abdominal abscesses

Adults

Abdominal right lower quadrant and midline

Not stated

1 month

PC (n =23)

Wound were closed with skin staples

DPC (n =26)

Wound packed with saline-soaked gauze, evaluated 3 days after surgery for closure with adhesive strip the next day if appropriate

Chatwiriya-charoen 2002[25]

Perforated appendicitis

Children

Abdominal right lower quadrant

Yes

5-14 days after discharge

PC (n =22)

Not stated

DPC (n =22)

Dressing daily and packed with Betadine gauze 5–10 days until suitable for suture

Lahat 2005[17]

Ileostomy closure

Adults

Ileostomy wound

Yes

2 weeks

PC (n =20)

Skin was closed with skin staples

DPC (n =20)

Wound packed with saline-soaked gauze and were not manipulated until day 3 for evaluation and closure on day 4 with nylon sutures if appropriate

Duttaroy 2009[7]

Peptic perforations, typhoid perforations, appendicular perforation/abscesses, penetrating or blunt abdominal injuries with gastrointestinal perforation, or intraperitoneal abscesses

Adults and children

Abdominal

Yes

4 weeks

PC (n =40)

Interrupted 2–0 polyamide sutures

DPC (n =37)

Packed with saline-soaked gauze for 48 hours then the wound was evaluated for suturing next day with interrupted 2–0 polyamide sutures

Chiang 2012[16]

Perforated appendicitis

Adults and children

Right lower quadrant

Yes

Not stated

PC (n =36)

Interrupted nylon sutures

DPC (n =34)

Packed with Betadine-soaked gauze and changed daily until day 5 or later for DPC

Khan 2012[18]

Complicated appendicitis (grossly inflamed, gangrenous, or perforated appendicitis)

Adults

Right lower quadrant

Yes

Not stated

PC (n =50)

Not stated

      

DPC (n =50)

Daily or twice dressing until postoperative day 3-5