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Table 1 Characteristics of the three study groups

From: The impact of early surgical intervention in free intestinal perforation: a time-to-intervention pilot study

   

<3 h

3–9 h

>9 h

 
 

N

n

Mean

SD

Median [IQR]

n

Mean

SD

Median [IQR]

n

Mean

SD

Median [IQR]

p-Value

Age

76

25

59,64

18,775

63 [50, 74]

36

64,36

14,934

65 [56.25;76.5]

15

68,8

14,586

69 [61;80]

0,205

Length of hospital stay

76

25

20,64

14,731

22 [10, 28]

36

28,75

32,056

17,5 [11;29]

15

20,27

14,235

16 [11;27]

0,921

Duration of surgery (minutes)

76

25

135,2

73,005

112 [97, 165.5]

36

126,58

68,393

112,5 [70;170.25]

15

127,07

47,596

135 [70; 160]

0,744

Ventilatory time (hours)

76

25

29,524

51,3765

6,2 [0.5, 19.2]

36

228,253

 

9,9 [5.175; 148.75]

15

105,94

186,3957

7,7 [3.9;276]

0,141

Katecholamins (within 24 h)

76

25

7102,32

15541,449

450 [0, 9330]

36

31294,5

80932,459

1911 [0; 9700]

15

4570,8

8733,606

0 [0; 2340]

0,604

Bikarbonate

76

25

84

123,929

0 [0, 155]

36

65,56

91,634

50 [0; 100]

15

40

54,116

0 [0;100]

0,656

Kristalloids

76

25

2876

1416,945

2600 [1600, 4125]

36

2564,17

1364,581

2525 [1562.5; 31^37.5]

15

1990

978,373

1800 [1500; 2100]

0,184

Kolloids

76

25

854

1951,384

500 [0, 1000]

36

326,39

421,813

0 [0; 500]

15

400

430,946

500 [0; 500]

0,13

Substitution of erythrocyte concentrates

76

25

276

465,725

0 [0, 1020]

36

283,33

411,617

0 [0; 990]

15

260

0

437,199 [0; 1200]

0,839

Thrombocyte concentrates

76

25

20

70,711

0

36

20,83

71,088

0

15

33,33

129,099

0

1

Fresh frozen plasma

76

25

100

322,749

0

36

187,5

432,497

0

15

133,33

296,808

0

0,322

Glucose substitution within24h

76

25

15,2

76

0

36

15,2

76

0

15

40

129,835

0

0,987

Bicarbonate substitution within 24 h

76

25

70

119,024

0 [0, 100]

36

48,53

101,865

0

15

53,33

104,312

0 [0; 50]

0,335

Kistralloid substitution within 24 h

76

25

2990,8

2348,709

2800 [1720, 3700]

36

3198,61

1712,078

2800 [2000; 4500]

15

2536,67

1155,649

2250 [1700; 3000]

0,79

Kolloid substitution within 24 h

76

25

380

505,8

0 [0, 500]

36

328,57

404,076

0 [0; 500]

15

833,33

1531,417

0 [0; 1000]

0,869

Erythrocyte concentrates within 24 h

76

25

108

285,657

0

36

233,33

424,937

0 [0; 300]

15

260

337,639

0 [0; 600]

0,056

Thrombocyte concentrates within 24 h

76

25

12

60

0

36

12

60

0

15

8,33

50

0

0,604

FFP within 24 h

76

25

48

132,665

0

36

177,78

390,685

0 [0; 350]

15

26,67

103,28

0

0,283

SAPS_II score after source control

76

25

42,36

15,508

43 [29.5, 50.5]

36

44,28

15,161

46 [31.25; 55.75]

15

41,53

13,674

38 [34; 46]

0,894

APACHE II score after soruce control

76

25

21,08

8,026

21 [14, 26]

36

21,86

6,69

21,5 [17.25; 26.5]

15

19,87

5,718

20 [16; 25]

0,79

SOFA score after source control

76

25

6,32

4,059

6 [3, 9.5]

36

7,28

3,377

7 [5; 10]

15

6,27

3,127

6 [4; 9]

0,479

Gastric reflux within 24 h (ml)

76

25

166

225,074

30 [0, 300]

36

266,94

436,347

100 [0; 400]

15

163,33

227,272

80 [0; 250]

0,57

  1. FFP fresh frozen plasma, SAPS Simplified Acute Physiology Score, APACHE Acute Physiology and Chronic Health Evaluation II-score, SOFA Sequential Organ Failure Assessment score