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Table 4 Logistic regression analyses predicting in-hospital mortality for non-RSCL patients

From: Damage control operations in non-trauma patients: defining criteria for the staged rapid source control laparotomy in emergency general surgery

Variablea

Unadjusted modela

Adjusted multivariable modelb

OR (95 % CI)

p-valuec

OR (95 % CI)

p-valuec

Preoperative inflammatory status:

 No inflammation

0.30 (0.12–0.71)

0.0060

1.00

-

 Sepsis

0.71 (0.31–1.62)

0.4146

0.18 (0.02–1.95)

0.1583

 Severe sepsis/septic shock

7.44 (3.04–18.17)

<0.0001

12.32 (1.19–127.33)

0.0350

Patient Characteristics:

 Male Gender

2.72 (1.14–6.47)

0.0240

23.98 (2.00–287.34)

0.0122

 Race, White

1.25 (0.47–3.32)

0.6579

0.25 (0.01–5.64)

0.3857

 Age (≥70)

4.13 (1.86–9.19)

0.0005

13.77 (1.30–145.70)

0.0293

 No comorbidities

1.48 (0.69–3.18)

0.3201

1.00

-

 1 comorbidity

0.001 (0.001–999.99)

0.9546

0.001 (0.001–999.99)

0.9132

 2 comorbidities

1.07 (0.284.09)

0.9181

0.04 (0.01–4.13)

0.1746

 ≥3 comorbidities

1.21 (0.55–2.66)

0.6299

0.07 (0.01–0.57)

0.0139

Preoperative metrics:

 Acidosis (pH ≤ 7.25)

3.94 (1.51–10.30)

0.0052

11.08 (1.02–120.64)

0.0484

 Lactate (≥3)

2.68 (1.06–6.82)

0.0378

0.62 (0.08–4.78)

0.6425

 Coagulopathy (INR ≥ 1.7)

2.08 (0.62–6.97)

0.2333

2.11 (0.22–20.43)

0.5183

 ASA score, 1 or 2

0.001 (0.001–999.99)

0.9672

1.00

-

 ASA score, 3

0.21 (0.08–0.57)

0.0022

999 (0.001–999.99)

0.9574

 ASA score, 4 or 5

10.10 (3.65–27.95)

<0.0001

999 (0.001–999.99)

0.9416

  1. RSCL rapid source control laparotomy, PRBC packed red blood cells, C Celsius, INR international normalized ratio, ASA American Society of Anesthesiologists
  2. aUnadjusted univariate analyses were used to test an independent variables’s predictive ability on in-hospital mortality
  3. bModel covariates for mortality were chosen by full selection
  4. c P-value of <0.05 significant