Skip to main content

Table 1 Comparison of necrotizing fasciitis by outcome (survivors versus non-survivors)

From: Pattern and predictors of mortality in necrotizing fasciitis patients in a single tertiary hospital

 

All patients (n = 331)

Survivors (n = 246)

Non- survivors (n = 85)

P *

Males

246 (74.3 %)

75 %

73 %

0.73

Age in yearsa

50.8 ± 15.4

47 ± 14

61.6 ± 14.3

0.001

Nationality

    

 Qatari

110 (33.2 %)

27.2 %

50.6 %

0.001

 Non-Qatari (Arabs)

73 (22.1 %)

20.3 %

27.1 %

 

 Others

148 (44.7)

52.4 %

22.4 %

 

Symptoms

    

 Swelling

237 (78 %)

76.4 %

82.3 %

0.28

 Pain/tenderness

208 (68.4 %)

72.4 %

57 %

0.01

 Fever

203 (67 %)

73.3 %

48 %

0.001

Laboratory findings

    

 Hemoglobin (g/dl)a

11 ± 2.7

11.4 ± 2.7

10.1 ± 2.6

0.001

 WBC(/μl)a

16.2 ± 8.6

16.4 ± 8.6

15.2 ± 8.6

0.28

 Platelet count (/μl)b

269 ± 201

273 ± 141

230 ± 158

0.02

 Sodium (mmol/l)a

133.5 ± 5.6

133.4 ± 5.4

133.9 ± 6

0.43

 Serum Creatinine (μmol/l)b

97 (26–1263)

91 (26–1189)

135 (26–1263)

0.001

 Serum Bilirubin(μmol/l)b

14.2 (3–381)

14 (3–233)

15 (4–381)

0.35

 Serum Glucosea

12.0 ± 7.8

12.5 ± 8.4

10.7 ± 5.4

0.07

 C-reactive proteina

221 ± 120

214 ± 120

232 ± 120

0.35

 Procalcitonin (<24 h)b ,c

10.5 (0.07-303)

3.3 (0.07-303)

9.8 (0.1-182)

0.28

Scoring

    

 SOFAb

9 (2–21)

9 (2–19)

12 (7–21)

0.001

 LRINECb

6 (1–13)

5 (1–13)

7 (2–13)

0.001

Site

    

 Lower limb/Thigh

175 (53 %)

53.3 %

51.8 %

0.81

 Perineum

81 (25 %)

23.6 %

27 %

0.52

 Abdominal/Groin

38 (11.5)

10.6 %

14 %

0.37

 Upper Limb

13 (3.9 %)

4.1 %

3.5 %

0.82

 Neck/Facial

21 (6.3 %)

7.3 %

3.5 %

0.21

 Chest/Breast

8 (2.4 %)

2.8 %

1.2 %

0.38

 Sacral

5 (1.5 %)

0.4 %

4.7 %

0.005

 Gluteus

3 (0.9 %)

1.2 %

0 %

0.30

 Histopathological confirmation

192 (58 %)

61 %

49.4 %

0.06

Morbidity

    

 Diabetes Mellitus

167 (52 %)

47 %

64 %

0.007

 Renal impairment

49 (15.2 %)

10 %

30 %

0.001

 Coronary Artery disease

46 (14.2 %)

11 %

25 %

0.001

 Trauma

43 (15.5 %)

18.2 %

8 %

0.04

Number of debridementb

2 (1–8)

2 (1–7)

2 (1–8)

0.22

Combined antibiotics(>2)

94(33.6 %)

49.3 %

28.2 %

0.001

Septic shock

76 (27.8 %)

19 %

51.4 %

0.001

ICU stay in daysb

5.5 (1–75)

5 (1–43)

9 (1–75)

0.002

Hospital stay in daysb

16 (2–295)

15 (2–295)

20.5(2–273)

0.02

  1. * = survivors vs. non-survivors, a = values in (mean ± SD), b = values in median and (range), c=<0.5ng/l low risk and >2.0 ng/l high risk sepsis