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Table 10 Meta-analysis about laparoscopic abdominal lavage

From: A historical review of surgery for peritonitis secondary to acute colonic diverticulitis: from Lockhart-Mummery to evidence-based medicine

 

Cirocchi

Ceresoli

Angenete

Marshall

All Hinchey

Hinchey III

Hinchey III

Hinchey III

Hinchey III

Post-operative mortality at index admission or within 30 days from index intervention

RR 1.33, 95% CI 0.37 to 4.74

RR 3.01, 95% CI 0.48 to 18.93

OR 0.93; 95% C.I. 0.23–3.82; P = 0.92

RR 1.34, 95% CI 0.59–3.04

RR 1.34, 95% CI 0.37 to 4.79

Mortality at 90 days

RR 1.27, 95% CI 0.60 to 2.69

Not performedj

OR 0.83; 95% C.I. 0.32–2.11; P = 0.69

RR 0.86, 95% CI 0.40–1.83

RR 0.86, 95% CI 0.40 to 1.84

Mortality at 12 months

RR 0.84, 95% CI 0.38 to 1.88

Not performedj

OR 0.74 P = 0.51

RR 0.54, 95% CI 0.38–0.76

 

Reoperation at index admission or within 30 days from index intervention

RR 1.93, 95% CI 0.71 to 5.22

RR = 1.40, 95% CI 0.71 to 4.90

OR 3.75, P = 0.006

RR 1.34, 95% CI 0.59–3.04

RR 3.03, 95% CI 1.16 to 7.89

At 90 days follow reoperations

Not analyzeda

Not performedj

NR

RR 1.71, 95% CI 0.85–3.43

NR

At 12 months follow reoperations

RR 0.57, 95% CI 0.39 to 0.86

Not performedj

OR 0.32, P = 0.0004

RR 0.54, 95% CI 0.38–0.76

NR

Intra-abdominal abscesses at index admission or within 30 days from index intervention

Not analyzedb

Not performedj

OR 3.50; 95% C.I. 1.79–6.86; P = 0.0003

NR

NR

Intra-abdominal abscesses at 90 days

RR = 2.54, 95% CI 1.34 to 4.83

Not performedj

NR

NR

NR

Wound infections

RR = 0.10, 95% CI 0.02 to 0.51

Not performedj

OR 0.14; 95% C.I. 0.04–0.45; P = 0.0009

NR

NR

Morbidity at 90 days

Not performedj

Not performedj

OR 1.70; 95% C.I. 1.00–2.87; P = 0.05

NR

NR

Presence of stoma at 12 months

RR = 0.50, 95% CI 0.14 to 1.75

Not performedj

OR 0.44 P = 0.27

NR

RR 0.50, 95% CI 0.14 to 1.76

Operating time

Not analyzedc

Not performedj

NR

NR

NR

Post-operative persistent peritonitis

Not analyzedd

Not performedj

NR

NR

NR

Post-operative secondary peritonitis

Not analyzede

Not performedj

NR

NR

NR

Length of post-operative hospital stay during index admission.

WMD −2.03, 95% CI−2.59 to−1.47

Not performedj

NR

NR

NR

Adverse events within 90 days by Dindo-Clavien grade I-II

Not analyzedf

Not performedj

NR

NR

NR

Adverse events within 90 days by Dindo-Clavien grade IIIa

Not analyzedg

Not performedj

NR

NR

NR

Adverse events within 90 days by Dindo-Clavien grade IIIb

RR 1.40, 95% CI 0.47 to 4.17

Not performedj

NR

RR 1.46, 95% CI 0.99–2.20

NR

Adverse events within 90 days by Dindo-Clavien grade IVa

RR 0.59, 95% CI 0.20 to 1.75

Not performedj

NR

NR

NR

Adverse events within 90 days by Dindo-Clavien grade IVb

RR 0.62, 95% CI 0.10 to 3.75

Not performedj

NR

NR

NR

Total length of hospital stays within 12 months.

Not analyzedh

Not performedj

NR

NR

NR

Quality of Life

Not analyzedi

Not performedj

NR

NR

NR

Post-operative ICU admission

NR

NR

NR

NR

RR 0.85, 95% CI 0.40 to 1.78

  1. NR not reported
  2. aTwo trials (LADIES and DILALA) reported this outcome, but the LADIES reported only the abscesses needing percutaneous drainage, differently the DILALA reported only the abscess underwent surgical reintervention
  3. bOnly one trial (SCANDIV) reported this outcome
  4. cThis outcome was reported in the SCANDIV although a definition of operating time was not provided. In the DILALA trial, the duration of surgery, and time between end of surgery and the end of anesthesia was reported. In the LADIES trial, the results of a comparative analysis were provided in the absence of the primary data. Because of the incongruous reports of operating time, for these reasons the analysis of this outcome was not performed
  5. dOnly the DILALA trial analyzed this outcome as persistent peritonitis
  6. eOnly the SCANDIV trial analyzed this outcome of persistent peritonitis
  7. fOnly the DILALA trial reported this outcome
  8. gOnly the DILALA trial reported this outcome
  9. hOnly the DILALA trial reported this outcome
  10. iAll the included trials reported this outcome; however, the data of quality of life questionnaires were not comparable
  11. jLack of data