Table 9 RCTs about abdominal laparoscopic lavage: characteristics

LADIES ClinicalTrials.gov Identifier: NCT01317485

Multicentre two-armed randomised trial: 34 teaching hospitals and eight academic hospitals in Belgium, Italy, and the Netherlands

The Netherlands

Patients with generalised purulent and faecal peritonitis from sigmoid diverticulitis

Clinical signs of peritonitis. Free gas on and/or diffuse fluid on CT LOLA arm: Only patients with purulent perforated diverticulitis without overt perforation

Dementia Previous sigmoidectomy Prior pelvic irradiation, Chronic treatment with high-dose steroids (>20 mg daily) Being aged younger than 18 years or older than 85 years Preoperative shock needing inotropic support Patients with Hinchey I and II Patients with Hinchey IV peritonitis or overt perforation were excluded from the DIVA group

LOLA arm: 264 DIVA arm: 212

LOLA arm: between July 2010, and the early termination of the trial February 2013

DILALA trial ISRCTN for clinical trials ISRCTN82208287

Multicentre randomised trial

Sweden- Denmark

Perforated non-faeculent diverticulitis

Hinchey grade III at diagnostic laparoscopy, i.e. free fluid

Hinchey grade I - II at laparoscopy i.e. no free fluid Hinchey grade IV at laparoscopy, i.e. gross faecal contamination. Other pathology than diverticulitis diagnosed as explanation of peritonitis

80

Between February 2010 until February 2014

SCANDIV ClinicalTrials.gov Identifier: NCT01047462

Multicentre randomised trial

Sweden- Norvey

Perforated non-faeculent diverticulitis

Patients with generalised peritonitis

Pregnancy Bowel obstruction

199

Between February 2010 until June 2014