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Table 5 Baseline demographic characteristics of the study patients

From: Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial

Male/female,
Age, median (IQRa), years
Septic shockb
World Society of Emergency Surgery Sepsis Severity Scorec
Calgary PIRO Scored
GCSe, median (IQR)
APACHE IIf, median (IQR)
Arterial pH, mean (95% CI)
Base deficit, median (IQR)
Lactate, median (IQR)
INRg, median (IQR)
Temperature, mean (95% CI)
APACHE-II scoref, mean ± SDd
SOFA scoreh, mean ± SDe
Charlson Comorbidity Index scorei, median (IQR)
Worst physiologic measurements prior to randomization, median (IQR)
 Systolic blood pressure, mmHg
 Temperature (injured patients), °C
 Temperature (sepsis patients), °C
 pH
 Lactate, mmol/L
 Base deficit, mmol/L
 INR
Fluid administration prior to randomization, median (IQR)
 PRBCj, units
 FFPk, units
 PRBC/FFP ratio
 Crystalloid, L
Patient location prior to OR admission—no. (%)
 Emergency department
 Hospital ward
 Intensive care unit
Vasopressors required prior to randomization—no. (%)
Hours from sepsis diagnosis to laparotomy, median (IQR)
  1. aIQR interquartile range
  2. bSeptic shock as defined by SESPS-3 guidelines [7]
  3. cWSESSS [8]
  4. dCPIRO [43]
  5. eGCS Glasgow Coma Score
  6. fAcute Physiology And Chronic Health Evaluation II
  7. gINR international normalized ratio
  8. hSOFA Sequential Assessment of Organ Failure [110]
  9. iCharlson Comorbidity Index [111]
  10. jPRBC packed red blood cells
  11. kFFP fresh frozen plasma