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Table 1 Clinical characteristics between mortality in the late amputation and survival in the amputation group

From: Risk factors for mortality in the late amputation of necrotizing fasciitis: a retrospective study

Variable Mortality in late amputation (n = 13) Survival in amputation (n = 22) p value
Mean age (years) 65.08 ± 10.94 66.35 ± 14.76 0.762
Clinical condition, no.(%)
 Wound 9 (69.2%) 9 (42.0%) 0.059
 Hemorrhagic bullae 7 (53.8%) 13 (35.4%) 0.001*
Comorbidity, no. (%)
 Diabetes mellitus 10 (76.9%) 8 (36.4%) 0.014*
 CKD 5 (38.5%) 10 (45.5%) 0.286
 Liver cirrhosis 1 (7.7%) 5 (22.7%) 0.327
 PAD 5 (38.5%) 2 (9.1%) < 0.001*
Admission data
 WBC count (× 103/μL) 13.9 (± 6.5) 14.8 (± 7.8) 0.693
 CRP (mg/dL) 191.9 (± 103.3) 134.1 (± 111.7) 0.012*
 Creatinine (mg/dL) 2.4 (± 1.5) 1.6 (± 0.8) 0.139
 Albumin (g/dL) 3.1 (± 0.6) 3.3 (± 0.6) 0.266
 Na (mmol/L) 133 (± 4.3) 134 (± 3.6) 0.125
 Lactate, mg/dL 33.9 (± 30.4) 23.2 (± 18.6) 0.086
LRINEC score > 8, n (%) 8 (61.5%) 8 (36.7%) < 0.001*
Bacteremia, n (%) 9 (69.2%) 8 (36.4%) 0.001*
Hospital stay (days) 41.2 (± 16.9) 33.7 (± 21.1)  
  1. Values are presented as mean ± standard deviation or number (%)
  2. PAD, peripheral artery disease, CKD chronic kidney disease, WBC white blood cell, CRP C-reactive protein, LRINEC Laboratory Risk Indicator for Necrotizing Fasciitis
  3. *p < 0.05