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Table 1 Clinical characteristics between mortality in the late amputation and survival in the amputation group

From: Risk factors for mortality in the late amputation of necrotizing fasciitis: a retrospective study

Variable

Mortality in late amputation (n = 13)

Survival in amputation (n = 22)

p value

Mean age (years)

65.08

± 10.94

66.35

± 14.76

0.762

Clinical condition, no.(%)

 Wound

9

(69.2%)

9

(42.0%)

0.059

 Hemorrhagic bullae

7

(53.8%)

13

(35.4%)

0.001*

Comorbidity, no. (%)

 Diabetes mellitus

10

(76.9%)

8

(36.4%)

0.014*

 CKD

5

(38.5%)

10

(45.5%)

0.286

 Liver cirrhosis

1

(7.7%)

5

(22.7%)

0.327

 PAD

5

(38.5%)

2

(9.1%)

< 0.001*

Admission data

 WBC count (× 103/μL)

13.9

(± 6.5)

14.8

(± 7.8)

0.693

 CRP (mg/dL)

191.9

(± 103.3)

134.1

(± 111.7)

0.012*

 Creatinine (mg/dL)

2.4

(± 1.5)

1.6

(± 0.8)

0.139

 Albumin (g/dL)

3.1

(± 0.6)

3.3

(± 0.6)

0.266

 Na (mmol/L)

133

(± 4.3)

134

(± 3.6)

0.125

 Lactate, mg/dL

33.9

(± 30.4)

23.2

(± 18.6)

0.086

LRINEC score > 8, n (%)

8

(61.5%)

8

(36.7%)

< 0.001*

Bacteremia, n (%)

9

(69.2%)

8

(36.4%)

0.001*

Hospital stay (days)

41.2

(± 16.9)

33.7

(± 21.1)

 
  1. Values are presented as mean ± standard deviation or number (%)
  2. PAD, peripheral artery disease, CKD chronic kidney disease, WBC white blood cell, CRP C-reactive protein, LRINEC Laboratory Risk Indicator for Necrotizing Fasciitis
  3. *p < 0.05