Determinants of treatment and outcomes of diverticular abscesses

Mali, Juha; Mentula, Panu; Leppäniemi, Ari; Sallinen, Ville

doi:10.1186/s13017-019-0250-5

World Journal of Emergency Surgery

Table 2 Basic characteristics and treatment results for patients with abscess diameter ≥ 40 mm and for matched patients

From: Determinants of treatment and outcomes of diverticular abscesses

Abscess ≥ 40 mm	Antibiotics (n = 79)	Drainage (n = 20)	p value	Matched antibiotics (n = 18)	Matched drainage (n = 18)	p value
Basic characteristics
Sex female	50 (63%)	8 (40%)	0.06^a	11 (61%)	7 (39%)	0.18^a
Age, years, median (IQR)	61 (52–73)	60 (48–69)	0.52^b	67 (55–78)	60 (50–69)	0.15^b
WBC, × 10⁹/l, median (IQR)	13.6 (10.1–15.6)	11.1 (8.5–13.9)	0.10^b	12.0 (9.2–15.3)	10.5 (8.4–13.1)	0.26^b
CRP, mg/l, median (IQR)	140 (97–231)	126 (44–277)	0.79^b	162 (50–235)	110 (39–270)	0.45^b
Any earlier diverticulitis	20 (25%)	8 (40%)	0.19^a	6 (33%)	8 (44%)	0.49^a
Multiple abscesses	15 (19%)	2 (10%)	0.51^c	1 (6%)	2 (11%)	1^c
Abscess size, mm, median (IQR)	51 (44–66)	60 (52–88)	0.007^b	58 (50–66)	58 (50–67)	0.95^b
Charlson Comobidity Index, median (IQR)	2 (1–4)	2 (1–4)	0.94^b	3 (1–6)	2 (1–4)	0.25^b
Corticosteroid medication	11 (14%)	4 (20%)	0.5^c	5 (28%)	4 (22%)	1^c
Outcomes
Overall failure	21 (27%)	7 (35%)	0.46^a	8 (44%)	6 (33%)	0.49^a
30-day mortality	4 (5%)	1 (5%)	1^c	1 (6%)	1 (6%)	1^c
Need of emergency surgery during initial admission or within 30 days	13 (17%)	6 (30%)	0.21^c	5 (28%)	5 (28%)	1^a
Readmission within 30 days of discharge	6 (14%)	2 (10%)	0.66^c	3 (17%)	2 (11%)	1^c
Recurrence of diverticulitis during follow-up^d	20 (32%), n = 62^e	1 (8%), n = 13^e	0.1^c	2 (17%), n = 12^e	1 (8%), n = 12^e	1^c
Complicated recurrence^d	13 (21%), n = 62^e	1 (8%), n = 13^e	0.44^c	1 (8%), n = 12^e	1 (8%), n = 12^e	1^c
Sigma resection later than 30 days after discharge^d	29 (47%), n = 62^e	9 (69%), n = 13^e	0.14^a	8 (44%), n = 12^e	9 (50%), n = 12^e	1^c
Temporary stoma	4 (5%)	1 (5%)	1^c	2 (17%), n = 12^e	1 (8%), n = 12^e	1^c
Permanent stoma	4 (5%)	1 (5%)	1^c	1 (8%), n = 12^e	1 (8%), n = 12^e	1^c
Hospital stay, days, median (IQR)	4 (3–8)	7 (3–13)	0.17^b	6 (3–10)	6 (3–12)	0.73^b

WBC white blood cell count, IQR interquartile range, CRP C-reactive protein
^aχ² test
^bMann-Whitney U test
^cFisher’s exact test
^dMedian follow-up 71 months (IQR 46–100 months) for all patients
^ePatients who died within 30 days or had emergency surgery during initial admission or within 30 days were removed from the total

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