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Table 2 Distribution of laboratory predictive variables of in-hospital mortality

From: Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study

Variables Total patients Dead Survivors RR p value
n 3137 n 280 n 2857
(100%) (8.9%) (91.1%)
Blood oxygen saturation level (SpO2) (%) in air
 > 92 2782 (88.7) 152 (54.3) 2630 (92.1) 0.15 (0.12–0.19) < 0.001
 90–91 198 (6.3) 66 (23.6) 132 (4.6) 4.58 (3.62–5.79) < 0.001
 85–89 99 (3.1) 41 (14.6) 58 (2.0) 5.26 (4.04–6.85) < 0.001
 < 85 21 (0.7) 9 (3.2) 12 (0.4) 4.93 (2.97–8.18) < 0.001
 Not reported 37 (1.2) 12 (4.3) 25 (0.9) NA NA
WBC (cells/mm3)
 > 12,000 1950 (62.2) 182 (65.0) 1768 (61.9) 1.13 (0.89–1.43) 0.30
 4000–12,000 1043 (33.2) 63 (22.5) 980 (34.3) 0.58 (0.44–0.76) < 0.001
 < 4000 94 (3.0) 29 (10.4) 65 (2.3) 3.74 (2.70–5.18) < 0.001
 Not reported 50 (1.6) 6 (2.1) 44 (1.5) NA NA
Platelet count (cells/ mm3)
 > 150,000 2606 (83.1) 183 (65.4) 2423 (84.8) 0.38 (0.31–0.49) < 0.001
 50,000–1,500,000 387 (12.3) 73 (26.1) 314 (11.0) 2.51 (1.96–3.20) < 0.001
 < 50,000 32 (1.0) 18 (6.4) 14 (0.5) 6.67 (4.81–9.24) < 0.001
 Not reported 112 (3.6) 6 (2.1) 106 (3.7) NA NA
INR
 > 3 23 (0.7) 12 (4.3) 11 (0.4) 6.06 (4.03–9.11) < 0.001
 1.2–3 296 (9.4) 72 (25.7) 224 (7.8) 3.32 (2.61–4.22) < 0.001
 < 1.2 1954 (62.3) 149 (53.2) 1805 (63.2) 0.69 (0.55–0.86) 0.001
 Not reported 864 (27.5) 47 (16.8) 817 (28.6) NA NA
CRP (mg/l)
 > 200 450 (14.3) 70 (25.0) 380 (13.3) 1.99 (1.55–2.56) < 0.001
 101–200 462 (14.7) 51 (18.2) 411 (14.4) 1.29 (0.97–1.72) 0.08
 5–100 946 (30.2) 69 (24.6) 877 (30.7) 0.76 (0.58–0.98) 0.04
 < 5 258 (8.2) 3 (1.1) 255 (8.9) 0.12 (0.04–0.37) < 0.001
 Not reported 1471 (46.9) 157 (56.1) 1314 (46.0) NA NA
Procalcitonin (ng/ml)  
 > 10 85 (2.7) 31 (11.1) 54 (1.9) 4.47 (3.30–6.06) < 0.001
 0.5–10 260 (8.3) 42 (15.0) 218 (7.6) 1.96 (1.44–2.64) < 0.001
 < 0.5 100 (3.2) 3 (1.1) 97 (3.4) 0.33 (0.11–1.01) 0.03
 Not reported 2692 (85.8) 204 (72.9) 2488 (87.1) NA NA
Lactate (mmol/l)
 >4 139 (4.4) 61 (21.8) 78 (2.7) 6.01 (4.79–7.54) < 0.001
 1–4 615 (19.6) 86 (30.7) 529 (18.5) 1.82 (1.43–2.31) < 0.001
 < 1 136 (4.3) 6 (2.1) 130 (4.6) 0.48 (0.22–1.07) 0.06
 Not reported 2247 (71.6) 127 (45.4) 2120 (74.2) NA NA
  1. All p values calculated using two-sided chi-square test
  2. RR: risk ratio, NA: not applicable, WBC: white blood count, INR: international normalised ratio, CRP; C-reactive protein