Table 2 Distribution of laboratory predictive variables of in-hospital mortality
From: Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study
Variables | Total patients | Dead | Survivors | RR | p value |
|---|---|---|---|---|---|
n 3137 | n 280 | n 2857 | |||
(100%) | (8.9%) | (91.1%) | |||
Blood oxygen saturation level (SpO2) (%) in air | |||||
> 92 | 2782 (88.7) | 152 (54.3) | 2630 (92.1) | 0.15 (0.12–0.19) | < 0.001 |
90–91 | 198 (6.3) | 66 (23.6) | 132 (4.6) | 4.58 (3.62–5.79) | < 0.001 |
85–89 | 99 (3.1) | 41 (14.6) | 58 (2.0) | 5.26 (4.04–6.85) | < 0.001 |
< 85 | 21 (0.7) | 9 (3.2) | 12 (0.4) | 4.93 (2.97–8.18) | < 0.001 |
Not reported | 37 (1.2) | 12 (4.3) | 25 (0.9) | NA | NA |
WBC (cells/mm3) | |||||
> 12,000 | 1950 (62.2) | 182 (65.0) | 1768 (61.9) | 1.13 (0.89–1.43) | 0.30 |
4000–12,000 | 1043 (33.2) | 63 (22.5) | 980 (34.3) | 0.58 (0.44–0.76) | < 0.001 |
< 4000 | 94 (3.0) | 29 (10.4) | 65 (2.3) | 3.74 (2.70–5.18) | < 0.001 |
Not reported | 50 (1.6) | 6 (2.1) | 44 (1.5) | NA | NA |
Platelet count (cells/ mm3) | |||||
> 150,000 | 2606 (83.1) | 183 (65.4) | 2423 (84.8) | 0.38 (0.31–0.49) | < 0.001 |
50,000–1,500,000 | 387 (12.3) | 73 (26.1) | 314 (11.0) | 2.51 (1.96–3.20) | < 0.001 |
< 50,000 | 32 (1.0) | 18 (6.4) | 14 (0.5) | 6.67 (4.81–9.24) | < 0.001 |
Not reported | 112 (3.6) | 6 (2.1) | 106 (3.7) | NA | NA |
INR | |||||
> 3 | 23 (0.7) | 12 (4.3) | 11 (0.4) | 6.06 (4.03–9.11) | < 0.001 |
1.2–3 | 296 (9.4) | 72 (25.7) | 224 (7.8) | 3.32 (2.61–4.22) | < 0.001 |
< 1.2 | 1954 (62.3) | 149 (53.2) | 1805 (63.2) | 0.69 (0.55–0.86) | 0.001 |
Not reported | 864 (27.5) | 47 (16.8) | 817 (28.6) | NA | NA |
CRP (mg/l) | |||||
> 200 | 450 (14.3) | 70 (25.0) | 380 (13.3) | 1.99 (1.55–2.56) | < 0.001 |
101–200 | 462 (14.7) | 51 (18.2) | 411 (14.4) | 1.29 (0.97–1.72) | 0.08 |
5–100 | 946 (30.2) | 69 (24.6) | 877 (30.7) | 0.76 (0.58–0.98) | 0.04 |
< 5 | 258 (8.2) | 3 (1.1) | 255 (8.9) | 0.12 (0.04–0.37) | < 0.001 |
Not reported | 1471 (46.9) | 157 (56.1) | 1314 (46.0) | NA | NA |
Procalcitonin (ng/ml) | |||||
> 10 | 85 (2.7) | 31 (11.1) | 54 (1.9) | 4.47 (3.30–6.06) | < 0.001 |
0.5–10 | 260 (8.3) | 42 (15.0) | 218 (7.6) | 1.96 (1.44–2.64) | < 0.001 |
< 0.5 | 100 (3.2) | 3 (1.1) | 97 (3.4) | 0.33 (0.11–1.01) | 0.03 |
Not reported | 2692 (85.8) | 204 (72.9) | 2488 (87.1) | NA | NA |
Lactate (mmol/l) | |||||
>4 | 139 (4.4) | 61 (21.8) | 78 (2.7) | 6.01 (4.79–7.54) | < 0.001 |
1–4 | 615 (19.6) | 86 (30.7) | 529 (18.5) | 1.82 (1.43–2.31) | < 0.001 |
< 1 | 136 (4.3) | 6 (2.1) | 130 (4.6) | 0.48 (0.22–1.07) | 0.06 |
Not reported | 2247 (71.6) | 127 (45.4) | 2120 (74.2) | NA | NA |