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Table 2 Physiologic characteristics of the patient groups

From: Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients?

Physiologic characteristicsnoHS noAbd (n = 16)HS noAbd
(n = 8)
HS Abd
(n = 18)
p value all groupsp value
(HS noAbd vs. HS Abd.)
I-FABP (pg/ml, ER)844.4 (530.0–1432.9)7292.3 (1282.5–11,159.5)28,637.0 (6372.4–55,550.0)< 0.00010.02
SBP (mm Hg, pre-hospital)130 (95–151)115 (88–129)70 (68–90)0.00040.02
SBP (mm Hg, ER)105 (86–120)100 (78–113)71 (61–106)0.110.40
heart rate (n/min, prehospital)91 (80–110)120 (110–121)116 (100–130)0.050.73
heart rate (n/min, ER)101 (90–110)115 (101–123)120 (88–132)0.290.98
shock index (prehospital)0.7 (0.5–1.0)1.0 (0.9–1.4)1.4 (1.3–1.8)0.00020.05
shock index (ER)1.0 (0.8–1.3)1.2 (1.0–1.4)1.4 (1.1–2.0)0.090.39
Fluid transfusion (ml, pre-hospital)1000 (650–1000)1250 (500–1750)1500 (1000–1500)0.280.88
Fluid transfusion (ml, ER)1000 (775–2250)3000 (1937.5–6375)2000 (1500–2500)0.020.08
PRBC transfusion within 24 h (Units)2 (1–5.5)11.5 (10.8–22.5)19 (13–27.8)< 0.00010.18
PRBC transfusion total (Units)6 (3.5–12.5)19.5 (15.5–32.3)25.5 (18–37.5)< 0.00010.44
FFP transfusion within 24 h (Units)0 (0–3)10 (5.8–17)15.5 (11.3–19)< 0.00010.19
FFP transfusion total (Units)0 (9–3)10 (5.8–19)17.5 (11.5–21.3< 0.00010.16
Hemoglobin (g/dl, ER)11.9 (11.4–13.5)6.6 (5.2–8.0)7.1 (5.7–8.4)< 0.00010.49
PTT (s, ER)28 (24.5–30)48 (38–51.5)38 (29–45)0.0020.1
INR (ER)1.1 (1–1.3)1.3 (1.2–1.8)1.3 (1.1–1.5)0.060.32
Fibrinogen (mg/dl, ER)190.5 (153–242.5)142 (116.3–176)186.5 (134–227.5)0.240.23
PLT count (× 103/μl, ER)186.5 (155.8–256.8)94 (51.3–137.8)178.5 (113.3–206.8)0.030.03
Hemostatic therapy (done, n, %)8 (50%)8 (100%)18 (100%)0.00031.0
Leukocyte count (U/nl)10.8 (9.5–13.5)9.9 (8.8–11)8.6 (6.7–10.8)0.140.47
Lactate (mmol/l, ER)2.4 (1.9–3.9)7.4 (6.4–10.6)8.5 (6.7–9.2)< 0.00010.98
pH value7.3 (7.2–7.4)7.4 (7.1–7.4)7.2 (7.1–7.2)0.030.26
Base deficit (mmol/l, ER)− 5.1 (−7.1–− 3.2)− 7.2 (− 11.8–− 1.9)− 10.1 (− 11.7–− 6.3)0.110.45
Temperature (°C, ER)36 (35.3–36.5)37 (35.9–37.5)36.1 (35.4–36.6)0.280.13
  1. Values are reported as median (interquartile range, IQR)
  2. ER, emergency room; FFP, fresh frozen plasma; HS Abd, hemorrhagic shock with abdominal injury; HS noAbd, hemorrhagic shock without abdominal injury; I-FABP, intestinal fatty acid-binding protein; INR, international normalized ratio; noHS noAbd, no hemorrhagic shock and no abdominal injury; PLT, platelets; PRBC, packed red blood cells; PTT, partial thromboplastin time; SBP, systolic blood pressure