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Table 4 Bivariate analyses of severe bleeding

From: Antithrombotic drugs do not increase intraoperative blood loss in emergency gastrointestinal surgery: a single-institution propensity score analysis

 Severe bleedingNon severe bleedingp value
Subjects1701014 
Age, years (range)77 (84–64)59 (73–33)<0.001
Gender, male84 (49.4)588 (58.0)0.037
Antithrombotic drugs33 (19.4)130 (12.8)0.030
 Antiplatelet drugs23 (13.5)105 (10.4)0.230
 Anticoagulant drugs14 (8.2)28 (2.8)0.001
Dual antithrombotic drugs4 (2.4)22 (2.2)0.781
Type of surgery   
 Gastrectomy9 (5.3)3 (0.3)< 0.001
 Patch repair duodenal ulcer7 (4.1)54 (5.3)0.707
 Intestinal surgery43 (25.3)285 (28.1)0.461
 Colorectal surgery67 (39.4)104 (10.3)< 0.001
 Stoma formation30 (17.6)73 (7.2)< 0.001
 Appendectomy7 (4.1)453 (44.7)<0.001
 Cholecystectomy7 (4.1)40 (3.9)0.834
Surgical approach  <0.001
 Laparotomy164 (96.5)591 (58.3) 
 Laparoscopy6 (3.5)423 (41.7) 
Comorbidities   
 Diabetes mellitus36 (21.2)94 (9.3.6)<0.001
 Renal failure20 (11.8)30 (3.0)<0.001
 Liver cirrhosis11 (6.5)15 (1.5)<0.001
 Coronary artery disease10 (5.9)55 (5.4)0.855
 Atrial fibrillation20 (11.8)36 (3.6)<0.001
 Cerebrovascular disease14 (8.2)43 (4.2)0.032
 Deep vein thrombosis7 (4.1)18 (1.8)0.075
 Hypertension97 (57.1)280 (27.6)<0.001
 Malignancy79 (46.5)192 (18.9)<0.001
Blood transfusion   
Red Blood Cell159 (93.5)0 (0.0)<0.001
 Amount (units)4 (2–6)0 (0–0)<0.001
Fresh frozen plasma81 (47.6)24 (2.4)<0.001
 Amount (units)0 (10–0)0 (0–0)<0.001
Platelet27 (15.9)4 (0.4)<0.001
 Amount (units)0 (0–0)0 (0–0)<0.001
Bleeding events21 (12.4)12 (1.2)<0.001
Thrombotic events9 (5.3)16 (1.6)0.006
Mortality36 (21.2)14 (1.4)<0.001
Operative time (min)136 (183–100)86 (121–63)<0.001
Length of stay (days)31 (53–17)10 (18–5)<0.001
Other complications   
 Surgical site infection57 (33.5)108 (10.7)<0.001
 Abscess50 (29.4)81 (8.0)<0.001
 Pneumonia35 (20.6)28 (2.8)<0.001
  1. Data are presented as number (percentage) or median (interquartile). One unit of red blood cells, fresh frozen plasma, and platelet are approximately 120 cc, 120 cc, and 20 cc, respectively