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Table 1 Patient characteristics at index necrosectomy

From: Open necrosectomy in acute pancreatitis–obsolete or still useful?

 

(n = 109)

Age at onset of symptoms, median (IQR), years

52 (42–61)

Time from onset of symptoms, median (IQR), days

36 (22–59)

 < 28 days from symptom onset

40 (36.7%)

Length of stay at intensive care unit, median (IQR), days

15 (1–24)

Male sex

96 (88.1%)

Co-morbidities

 Heart disease

22 (20.2%)

 Pulmonary disease

10 (9.2%)

 Mild renal insufficiency

4 (3.7%)

 Diabetes

11 (10.1%)

 Liver cirrhosis

2 (1.8%)

 Chronic pancreatitis

3 (2.8%)

 None of the above

66 (60.6%)

Etiology

 Alcohol

62 (56.9%)

 Biliary

25 (22.9%)

 Idiopathic

11 (10.1%)

 Other*

11 (10.1%)

Preoperative computed tomography

Pancreatic necrosis

 

  Not assessable

45 (41.3%)

  < 30%

31 (28.4%)

  30–50%

11 (10.1%)

  > 50%

22 (20.2%)

Distant pancreatic necrosis

98 (89.9%)

Complex necrosis

66 (60.6%)

Disconnected left pancreatic remnant

34 (31.2%)

Previous organ failure

 No organ failure

32 (29.4%)

 < 48 h organ failure

7 (6.4%)

 > 48 h organ failure

70 (64.2%)

Previous interventions of necrosis

 Fine-needle aspiration

31 (28.4%)

 Percutaneous drainage

28 (25.7%)

 Endoscopic drainage§

7 (6.4%)

 Surgical drainage||

11 (10.1%)

 Drainage duration, median (IQR), days

9 (6–14)

CRP, median (IQR)#

167 (89–290)

WBC count, median (IQR)#

12.6 (9.4–21.3)

Intra-operative findings

 Infected pancreatic necrosis

85 (78.0%)

 Disconnected left pancreatic remnant

13 (11.9%)

Resection of pancreas during index necrosectomy

12 (11.0%)

  1. IQR interquartile range, CRP C-reactive protein, WBC white blood cell
  2. *Other: post-ERCP (6), postoperative (2), post-endoscopic (1), hypertriglyceridemia (1) and drug-induced (1)
  3. Local necrosis around pancreas, distant necrosis also in left/right paracolic gutter and/or retromesenteric area
  4. Necrosis extending to both paracolic gutters or either of the paracolic gutters and the retromesenteric area
  5. §Pseudocyst gastrostomy or transpapillary canalization
  6. ||Surgical canalization of necrosis in patients with existing abdomen treatment
  7. Percutaneous or surgically placed drainage
  8. #Within 24 h of index necrosectomy. CRP expressed as mg/L. WBC count expressed as 1 × 109/L. Two CRP values and one WBC count were not taken 24 h prior to operation, and thus, the last available CRP value and WBC count prior to first necrosectomy, respectively, was used