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Table 3 Multivariable logistic regression analysis for in-hospital mortality

From: Association of pre-operative chronic kidney disease and acute kidney injury with in-hospital outcomes of emergency colorectal surgery: a cohort study

 

Adjusted odds ratio (95% CI)

P value

Exposure groups

 (i) CKD(-)AKI(-)

1 (reference)

 

 (ii) CKD(-)AKI(+)

2.54 (1.90–3.40)

< 0.001

 (iii) CKD(+)AKI(-)

1.29 (0.90–1.85)

0.166

 (iv) CKD(+)AKI(+)

2.86 (1.54–5.32)

0.001

 (v) ESRD

2.76 (1.55–4.93)

0.001

Covariates

 Age (per 1 year)

1.03 (1.02–1.05)

< 0.001

 Sex (men vs. women)

1.39 (1.00–1.93)

0.051

 Type of surgery

  

  Surgery for acute pan-peritonitis

1 (reference)

 

  Colectomy

1.67 (1.14–2.45)

0.009

  Colostomy

2.40 (1.38–4.17)

0.002

  Rectal resection

1.68 (0.98–2.87)

0.057

 Use of laparoscopy (yes vs. no)

0.22 (0.07–0.71)

0.012

 Indication for surgery

  

   Peritonitis or perforation

2.69 (0.55–13.13)

0.220

   Obstruction

4.06 (0.93–17.80)

0.063

   Bleeding or diverticulosis

1 (reference)

 

   Others

2.40 (0.51–11.23)

0.266

 Presence of colorectal cancer (yes vs. no)

0.92 (0.62–1.35)

0.671

 Body mass index (per 1 kg/m2)

0.94 (0.91–0.98)

0.001

 Comorbidities (yes vs. no)

  

  Diabetes

1.24 (0.96–1.61)

0.095

  Heart failure

1.66 (0.85–3.24)

0.135

  Chronic pulmonary disease

1.14 (0.59–2.21)

0.699

  Chronic liver disease

1.31 (0.71–2.40)

0.383

  Cancer (except for colorectal cancer)

1.81 (1.32–2.46)

< 0.001

 Blood test results at admission

  

  White blood cell count (per 1000/μl)

1.01 (0.98–1.04)

0.478

  Hemoglobin (per 1 g/dl)

0.90 (0.85–0.95)

< 0.001

  Platelet count (per 10,000/μl)

0.98 (0.96–0.99)

0.020

  Total protein (per 1 g/dl)

0.88 (0.80–0.96)

0.005

  Total bilirubin (per 1 mg/dl)

0.95 (0.74–1.23)

0.700

  C-reactive protein (per 1 mg/dl)

1.00 (0.99–1.01)

0.588

  1. AKI acute kidney injury, CKD chronic kidney disease, CI confidence interval, eGFR estimated glomerular filtration rate, ESRD end-stage renal disease