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Table 2 Clotting factor activity and levels in patient cohorts and adult controls

From: Trauma induced clotting factor depletion in severely injured children: a single center observational study

 

SI

MI

 

CO

 

Activity/level

Median

IQR

Median

IQR

p*

Median

IQR

p*

Fibrinogen (mg/dl)

198

80-242

239

195-253

0.20

296

204-324

0.034

FII

67

53-90

82

76-114

0.028

122

112-144

< 0.001

Ca (mmol/l)

2.23

2.13-2.36

2.30

2.25-2.40

0.38

2.30

2.30-2.40

0.36

FV

76

47-85

92

82-99

0.028

123

100-142

0.002

FVII

71

63-97

89

75-107

0.16

114

100-152

0.009

FVIII

235

91-320

197

164-238

0.72

108

89-133

0.17

FIX

84

67-103

80

73-107

0.72

110

90-114

0.043

FX

70

61-85

79

65-115

0.33

122

96-140

0.001

FXI

112

80-122

93

77-119

0.72

106

97-119

0.97

FXII

107

66-132

98

67-117

0.65

99

90-104

0.90

FXIII

67

62-87

90

77-102

0.021

102

79-115

0.006

  1. The clotting factor profiles of severely injured children (SI, n = 8) were compared with those of children with minor injury (MI, n = 8) and an adult control group (CO, n = 10). Coagulation factor activity is given as a percentage, except for fibrinogen and calcium (Ca). All variables represent median values together with interquartile range (IQR, 25th to 75th percentile)
  2. *Mann-Whitney U test versus SI