Table 2 Diagnostic criteria of COVID-19^a

Diagnostic basis

Outside Hubei Province: two of the clinical manifestations with at least one of the epidemiological histories, three of the clinical manifestations without epidemiological history

Suspected patient in Hubei Province with CT findings of pneumonia

Suspected or clinically confirmed patients with at least one pathogenic evidence

Epidemiological investigation

1. Travel to or residence in Wuhan in the 14 days prior to symptom onset;

2. Close contact^b with SARS-CoV-2 infection (rRT-PCR positive) within 14 days before onset;

3. Exposed to patients from Wuhan and surrounding areas, or from a community with patients who reported fever or respiratory symptoms14 d before onset;

4. Clustering outbreak.

-

-

Clinical manifestations and CT scan

1. Fever and/or respiratory symptoms;

2. Imaging characteristics of COVID-19(CT: multiple small plaque shadows and interstitial changes in early stage, which are obvious in the peripheral lung, and then develop into multiple ground-glass shadows and infiltration shadows in both lungs, and lung consolidation may occur in severe cases);

3. The total number of white blood cells in the early stage is normal or decreased, and the lymphocyte count is decreased

-

-

Pathogenic evidence

NULL

NULL

1. Detection of SARS-CoV-2 in respiratory specimens and sera by rRT-PCR assays;

2. By virus DNA sequencing, respiratory or blood samples DNA sequence highly homologous with SARS-CoV-2.