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Table 5 Factors associated with postoperative mortality

From: Predictors of mortality following emergency open colectomy for ischemic colitis: a single-center experience

Variables Univariate analysis Multivariate analysis
In-hospital postoperative mortality Odds ratio (95%CI) p value Adjusted odds ratio (95%CI) p value
Age > 75 years [n (%)] 27 (79.4) 2.23 (0.83–5.96) 0.163   
Age > 80 years [n (%)] 14 (77.8) 1.71 (0.51–5.75) 0.571   
Age, years (per unit increase) NA 1.02 (0.99–1.06) 0.098 1.03 (0.98–1.09) 0.157
Female [n (%)] 44 (71) 1.28 (0.51–3.18) 0.641   
ASA score > III [n (%)] 21 (80.8) 2.29 (0.76–6.84) 0.211   
Pancolic ischemia [n (%)] 35 (70) 1.08 (0.45–2.61) 1   
Obesity [n (%)] 7 (63.6) 1.32 (0.35–4.92) 0.733   
BMI (per unit increase) NA 1.01 (0.92–1.12) 0.696   
Hypoalbuminemia (< 3.5 g/dL) [n (%)] 4 (80) 1.83 (0.19–17.18) 1   
Lactates > 2.5 mmol/L [n (%)] 56 (76.7) 4.39 (1.58–12.18) 0.006 11.85 (1.6485.17) 0.014
Preoperative hemoglobin level (per unit increase) NA 1 (0.83–1.20) 0.973   
Diabetes [n (%)] 56 (71.8) 1.98 (0.65–5.97) 0.244   
Severe coronary disease [n (%)] 50 (71.4) 1.5 (0.56–3.97) 0.449   
COPD [n (%)] 50 (67.6) 1.44 (0.47–4.54) 0.596   
Kidney failure [n (%)] 47 (67.1) 1.47 (0.51–4.34) 0.611   
Hypertension [n (%)] 17 (60.7) 1.72 (0.68–4.38) 0.329   
Smoking [n (%)] 43 (67.2) 1.35 (0.51–3.57) 0.636   
Comorbidity > 1 [n (%)] 33 (78.6) 2.29 (0.90–5.78) 0.115 1.81 (0.33–9.9) 0.490
Time from signs/symptoms onset to surgery > 12 h [n (%)] 60 (84.5) 19.63 (6.02–63.97) < 0.0001 34.99 (7.14171.33) < 0.0001
Presence of aneurysmatic rupture* [n (%)] 8 (61.5) 2 (0.44–9) 0.451   
EVAR surgery* [n (%)] 4 (44.4) 0.2 (0.038–1.03) 0.085   
AS [n (%)] 24 (70.6) 1.11 (0.44–2.78) 1   
Total colectomy [n (%)] 35 (70) 1.08 (0.45–2.61) 1   
Preoperative vasopressor agents [n (%)] 47 (78.3) 3.21 (1.29–8) 0.019 2.54 (0.20–31.12) 0.466
Intraoperative vasopressor agents [n (%)] 55 (74.3) 2.89 (1.04–8) 0.037 6.37 (0.87–46.6) 0.068
Sepsis [n (%)] 32 (84.2) 3.71 (1.33–10.32) 0.012 2.31 (0.61–8.79) 0.218
Low output syndrome [n (%)] 5 (100) 1.48 (1.28–1.71) 0.125 3.83 (0.3–48.97) 0.301
Postoperative acute kidney injury [n (%)] 39 (76.5) 2.12 (0.87–5.17) 0.118 5.09 (1.1322.8) 0.033
Operative time, min (per unit increase) NA 1 (0.99–1.01) 0.493   
Blood loss > 500 mL [n (%)] 45 (78.9) 3.18 (1.28–7.89) 0.013 2.48 (0.68–9.05) 0.169
Open abdomen needed [n (%)] 4 (100) 1.47 (1.27–1.7) 0.172 0 (0–0) 0.999
ICMR score (per unit increase) NA 1.37 (0.89–2.12) 0.146 2.85 (0.91–8.91) 0.072
  1. ASA American Society of Anesthesiologists, AS for aortic surgery, COPD for chronic obstructive pulmonary disease, EVAR endovascular aortic repair, ICMR Ischemic Colitis Mortality Risk
  2. *n = 34