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Table 1 Definition of multiple organ dysfunction syndrome (MODS), acute respiratory distress syndrome (ARDS), and sepsis per included article

From: Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review

Author

MODS

ARDS

Sepsis

Lauwers et al. [12]

≥ 3 failing organs in a sequential pattern

As reported by Petty TL, Fowler AA (1982) Another look at ARDS. Chest 82:98 [61]

Leukocytosis, sustained fever (> 38.5 °C) and identification of a focus of infection either with systemic impact or positive blood cultures

Regel et al. [13]

As reported by Goris RJA, Nuytink HKS, Redl H: Scoring systems and predictors of ARDS and MOF. [62]

Goris RJA, Nuytink HKS, Redl H: Scoring systems and predictors of ARDS and MOF. [62]

Not mentioned

Aufmkolk et al. [14]

≥ 3 failing organs for ≥ 3 sequential days

Not defined

Positive blood culture + ≥ 2 of the following: 36 < Temp. > 38; 4000 < leukocytes > 12,000 or left shift > 10%; heart rate > 90/min; respiratory rate > 20/min or pCO2 < 32 mmHg

Dereeper et al. [15]

Acute renal failure was defined as a blood urea nitrogen (BUN) > 40 and/or creatinine > 2 mg/dl; hepatic failure by a bilirubin > 2 mg/dl or transaminases > 80 IU/l; coagulation abnormalities by a platelet count < 100,000/mm3 with either a prothrombin time < 60% of the normal value or an activated partial thromboplastin time > 80 s.

Acute respiratory failure by a PaO2/FiO2 ratio < 250 mmHg or requirement for mechanical ventilation for > 24 h for a respiratory problem

Not mentioned

Nast-Kolb et al. [17]

≥ 2 failing organs for ≥ 3 days (central nervous system not included)

European-American Consensus Conference on ARDS

A source of infection (positive blood culture) plus two or more of the following parameters: temperature 36 (°C) or 38; leukocytes 4000 (nL) or 12,000 or immature neutrophils 10%; heart rate > 90 (beats/min); and respiratory rate > 20 (breaths/min) or pCO2 > 32 mm Hg

Hadfield et al. [16]

Not defined

Not defined

Not defined

Ruiz et al. [41]

Not defined

Not defined

Sequential organ failure assessment (SOFA) score

Ciesla et al. [19]

Denver MOF scoring system

Not defined

Not defined

Zhang et al. [20]

Not defined

Not defined

Not defined

Di Saverio et al. [22]

Not defined

Not mentioned

Not defined

Chen et al. [21]

Not defined

Not defined

Not defined

Dehne et al. [34]

Not defined

Not mentioned

Not mentioned

Van Wessem and Leenen [23]

Denver multiple organ failure (MOF) scoring system

Berlin criteria

Not mentioned

Van Wessem and Leenen [32]

Denver MOFscoring system

Berlin criteria

Not defined

  1. “Not mentioned” means that this particular condition is not included in the article’s analyses. “Not defined” means that this condition is used, but its exact definition is not described