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Table 2 Characteristics of studies included in a review of mortality in polytrauma patients admitted to the ICU

From: Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review

Author and year of publication

Study population

Number of included patients

Location

Study duration

Mortality-related outcome

Lauwers et al. (1986) [12]

Blunt trauma, alive ≥ 1 h after ICU-admission, ISS > 25

130

Antwerp, Belgium

Jan 1982 –Feb 1984

Percentages

Hervé et al. (1987) [25]

All

167

Créteil, France

1969 and 1979

Percentages

Kivioja (1989) [26]

All

1169

Helsinki, Finland

1966–1984

Percentages

Goins et al. (1991) [27]

All

2911

Baltimore, USA

July 1985–June 1988

Absolute numbers

Regel et al. (1995) [13]

ISS > 20, ≥ 3 injuries

3406

Hannover, Germany

1972–1991

Percentages, per decade

Regel et al. (1996) [36]

ISS > 20, age 15–65,

 

Hannover, Germany

1986–1995

Percentages

  

342

   

Aufmkolk et al. (1997) [14]

ISS ≥ 18, divided in ≥ 65 and < 65 years, >16 years

1154

Essen, Germany

1975–1994

Percentages per age group

Dereeper et al. (1997) [15]

All, children/adults reported separately

97

Brussels, Belgium

1994–1995

Absolute numbers

Pape et al. (1999) [43]

Multiple blunt trauma, ISS > 20, no referrals

61

Hannover, Germany

Oct 1994–Apr 1997

Absolute numbers and percentage

Rixen et al. (2000) [39]

> 16 years, ISS > 16, ICU with cardiorespiratory monitoring

80

New Jersey, USA

N/A

Percentages

Nast-Kolb et al. (2001) [17]

ISS ≥ 16, alive ≥ 24 h after admission

1361

Essen, Germany

1975–1999

Percentages from total population, per 5 years

Hadfield et al. (2001) [16]

All

101

Bristol, UK

1996–1998

Absolute numbers, partly also percentages

Stiletto et al. (2001) [38]

ISS > 15, CCO-measurement

20

Marburg, Germany

1997–1999

Percentages

Ruiz et al. (2013) [41]

Polytraumatized and severely traumatized older than 18 years

72

Puente alto, Chili

2011

Absolute numbers and percentages

Ruscelli et al. (2014) [42]

ISS > 15, ICU admission, death in emergency ward,

747

Cesena, Italy

2007–2009

Absolute numbers and percentages

Ciesla et al. (2005) [19]

ISS > 15, alive > 48 h after trauma, > 15 years

1344

Denver, USA

May 1992–Dec 2003

Absolute numbers and percentages

Dresing et al. (2007) [56]

Age ≥ 18 years, ISS > 15

30

Goettingen, Germany

N/A

Absolute numbers and percentages

Probst et al. (2009) [28]

Blunt trauma

4849

Hannover, Germany

1975–2004

Percentages

Wafaisade et al. (2011) [29]

No missing data, no mild injury

29829

Cologne, Germany

2093–2008

Percentages

Zhang (2011) [20]

All

163

Congqing, China

2006–2009

Absolute numbers

Dewar et al. (2013) [30]

ISS > 15, age > 18 years, AIS < 3, survival > 48 h, no nonmechanical traumas

140

Newcastle, Australia

Dec 2005–Dec 2010

Absolute numbers and percentages

Di Saverio et al. (2014) [22]

ISS > 16

2935

Bologna, Italy

1996–2010

Percentages

Chen et al. (2014) [21]

All

80

Hangzhou, China

Jan 2009–Jun 2013

Absolute numbers

Fröhlich et al. (2014) [31]

ISS > 15, complete data for MOF

31154

Cologne, Germany

2002–2011

Percentages

Dehne et al. (2014) [34]

“Polytraumatized patients”

30

Giessen, Germany

N/A

Absolute numbers

Freitas and Franzon (2015) [40]

“Multiple trauma patients”

117

Sao José, Brazil

Apr 2013–Jul 2014

Absolute numbers

Mazandarani et al. (2016) [37]

Multiple trauma, age > 14 years mortality > 4 h on arrival in ICU.

152

Tehran, Iran

2011–2012

Absolute numbers

Brilej et al. (2017) [33]

ISS > 17, injuries to single region AIS 5, injuries to a single region and abnormal vital signs.

493

Berlin, Germany

2006–2014

Percentages

Van Wessem and Leenen (2018) [23]

Age ≥ 15 years, ISS > 15, no asphyxiation, burns, drowning, and isolated TBI

157

Utrecht, The Netherlands

Nov 2013–Nov 2016

Percentages

Van Wessem and Leenen (2018) [32]

Age ≥ 15 years, ISS > 15, survival > 48 h, no asphyxiation, burns, drowning, and isolated TBI

241

Utrecht, The Netherlands

Nov 2013–April 2018

Absolute numbers and percentages

  1. ISS Injury Severity Score, ICU intensive care unit, TBI traumatic brain injury, AIS abbreviated injury scale, MOF multiple organ failure, N/A not announced