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Table 1 Summary of patient characteristics and coagulation tests of the dead and surviving patients

From: Impact of fibrinogen level on the prognosis of patients with traumatic brain injury: a single-center analysis of 2570 patients

 

Died (%)

Survived (%)

Total (%)

P valuea

N

198 (100.0%)

2372 (100.0%)

2570 (100.0%)

 

Age (mean ± SD)

56.25 ± 17.81

47.90 ± 16.10

48.54 ± 16.38

< .001

Sex

   

.391

 Male

154 (77.8%)

1780 (75.0%)

1934 (75.3%)

 

 Female

44 (22.2%)

592 (25.0%)

636 (24.7%)

 

Mechanism of injury

    

 Traffic accident

119 (60.1%)

1346 (56.7%)

1465 (57.0%)

.090

 Fall

20 (10.1%)

358 (15.1%)

378 (14.7%)

 

 Stumble

44 (22.2%)

408 (17.2%)

452 (17.6%)

 

 Blow to head

6 (3.0%)

104 (4.4%)

110 (4.3%)

 

 Others

9 (4.5%)

156 (6.6%)

165 (6.4%)

 

Pupillary reactions

    

 Both reacting

103 (52.0%)

2145 (90.4%)

2248 (87.5%)

< .001

 One reacting

50 (25.3%)

183 (7.7%)

233 (9.1%)

 

 None reacting

45 (22.7%)

44 (1.9%)

89 (3.5%)

 

GCS at admission

6.73 ± 3.31

11.34 ± 3.49

10.98 ± 3.69

< .001

 ≤8

145 (73.3%)

586 (24.7%)

731 (28.5%)

< .001

 9-12

36 (18.2%)

653 (27.5%)

689 (26.8%)

 

 13-15

17 (8.6%)

1133 (47.8%)

1150 (44.7%)

 

CT findings

    

 IPH or brain contusion

162 (81.8%)

1642 (69.2%)

1804 (70.2%)

< .001

 SDH

104 (52.5%)

684 (28.8%)

788 (30.7%)

< .001

 EDH

32 (16.2%)

662 (27.9%)

694 (27.0%)

< .001

 DAI

19 (9.2%)

52 (2.2%)

71 (2.8%)

< .001

Multiple body injuries

13 (6.6%)

134 (5.6%)

147 (5.7%)

.594

 Face

1 (0.5%)

14 (0.6%)

15 (0.6%)

1.000

 Thorax

11 (5.6%)

92 (3.9%)

103 (4.0%)

.333

 Abdomen

2 (1.0%)

8 (0.3%)

10 (0.4%)

.385

 Extremities

2 (1%)

35 (1.5%)

37 (1.4%)

.828

 External

1 (0.5%)

3 (0.1%)

4 (0.2%)

.719

ISSb

22.33 ± 6.12

14.77 ± 7.02

15.35 ± 7.24

< .001

INR

1.16 ± 0.24

1.06 ± 0.13

1.07 ± 0.14

< .001

PT (s)

13.44 ± 2.71

12.161.55

12.26 ± 1.70

< .001

APTT (s)

31.19 ± 14.65

27.30 ± 7.20

27.60 ± 8.09

< .001

FIB (g/L)

2.06 ± 1.16

2.58 ± 1.13

2.54 ± 1.14

< .001

D-dimer (mg/L)

10.52 ± 14.67

6.90 ± 10.73

7.18 ± 11.12

< .001

PLT (× 109/L)

156 ± 61

177 ± 67

176 ± 67

< .001

Hb (g/L)

124 ± 25

131 ± 21

131 ± 21

< .001

HCT (%)

36.44 ± 6.92

38.36 ± 5.69

38.21 ± 5.82

< .001

  1. GCS Glasgow Coma Scale, ISS Injury Severity Score, PLT platelet, INR international normalized ratio, PT prothrombin, APTT activated partial thromboplastin time, FIB fibrinogen, EDH epidural hematoma, SDH subdural hematoma, IPH intraparenchymal hemorrhage, DAI diffuse axonal injury
  2. aP values not adjusted for multiple comparisons. Statistical significance determined by chi-square test, Student’s t test or Mann-Whitney tests
  3. bISS = AIS12 + AIS22 + AIS32, it is the sum of squares for the highest values in each of the three most severely injured body regions