| Disease | Author | Year | Number of patients | Study design | Timing | Morbidity | Mortality |
|---|---|---|---|---|---|---|---|
| Pancreatitis | Mentula [47] | 2010 | 26 | Retrospective | DL within 4 days vs. later | nr | 18% vs. 100% |
| Davis [48] | 2013 | 45 | Retrospective |
16 pts DL after 3.1 h from ACS diagnosis 3.3 h in BMI > 30 vs. 2.8 h in BMI < 30 | 43% (ECF or EAF) |
Overall 24.1% 10% vs. 33.3% | |
| De Waele [49] | 2016 | 33 (27 pts with primary ACS) | Retrospective | DL within 3.1 h from ACS diagnosis | 24% |
At 28 days: 36% At 1 year: 55% | |
| Burn | Ramirez [50] | 2018 | 46 (27 pts with ACS during initial resuscitation) | Retrospective | DL within 13 h from ACS diagnosis vs. later (analysis of the 27 pts with ACS during initial resuscitation) | nr | 30% vs. 67% (p = 0.03) |