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Table 1 Characteristics of the patients

From: Early administration of fibrinogen concentrate is associated with improved survival among severe trauma patients: a single-centre propensity score-matched analysis

 Control group
n = 110
FC group
n = 38
p value
Age (year)54 (39–71)53 (32–72)0.565
Gender, male86 (78.2%)20 (52.6%)0.005
Blunt trauma106 (96.4%)36 (94.7%)0.647
Mechanism of the injury
 Traffic accident (in the car)29 (26.4%)13 (4.2%)0.313
 Traffic accident (pedestrian)29 (26.4%)13 (34.2%)
 Fall39 (35.5%)10 (26.3%)
 Invert6 (5.5%)0 (0.0%)
 Stab wound/cutting3 (2.7%)2 (5.3%)
 Others4 (3.6%)0 (0.0%)
Injury to the admission to ED
 0–30 (min)12 (10.9%)9 (23.7%)0.138
 30–60 (min)64 (58.2%)21 (55.3%)
 60–90 (min)21 (19.1%)3 (7.9%)
 90– (min)13 (11.8%)5 (13.2%)
Revised trauma score6.72 (5.03–7.84)5.68 (4.09–6.08)< 0.001
Probability of survival0.842 (0.630–0.943)0.567 (0.230–0.832)< 0.001
Vital signs on the admission to ED
 Heart rate (per min)86 (72–105)110 (86–120)0.010
 Glasgow Coma Scale11 (6–14)6 (3–13)0.035
 Systolic Blood Pressure (mmHg)120 (99–151)93 (68–137)0.014
 Respiratory rate (per min)22 (16–25)21 (17–30)0.489
Injury severity score25 (20–32)34 (25–41)< 0.001
Abbreviated injury scale
 Head/neck4 (1–5)4 (0–5)0.264
 AIS face0 (0–0)0 (0–1)0.482
 AIS chest3 (0–4)3 (0–4)0.104
 AIS abdomen0 (0–2)0 (0–3)0.065
 AIS extremity1 (0–3)2 (0–3)0.047
 AIS external1 (0–1)1 (0–1)0.082
Blood gas analysis
 pH7.35 (7.30–7.38)7.24 (7.11–7.35)< 0.001
 Base deficit (mmol/L)2.5 (0.3–5.4)6.95 (2.7–14.63)< 0.001
 Lactate (mmol/L)3.2 (2.3–4.7)5.8 (3.6–10.0)< 0.001
Laboratory tests
 Platelet (× 103/μL)200 (147–235)193 (146–234)0.632
 PT-INR1.06 (0.98–1.158)1.22 (1.12–1.40)< 0.001
 Fibrinogen (mg/dL)193 (159–235)156 (137–219)0.034
 FDP (μg/mL)76.4 (30.0–165.0)99.5 (45.0–188.0)0.349
 D-dimer (μg/mL)47.8 (19.5–104.2)58.3 (28.3–104.9)0.633
  1. FC fibrinogen concentrate, ED emergency department, AIS abbreviated injury scale, PT-INR prothrombin time-international normalised ratio, FDP fibrin/fibrinogen degradation products