Early administration of fibrinogen concentrate is associated with improved survival among severe trauma patients: a single-centre propensity score-matched analysis

Table 3 Hemostatic treatments and transfusion amounts in the propensity-matched groups

	Control group n = 31	FC group n = 31	p value
Interventions to emergency haemostasis	5 (16.1%)	10 (32.2%)	0.138
Thoracotomy and/or laparotomy	3 (9.7%)	8 (25.8%)	0.096
Transarterial embolization	3 (9.7%)	2 (6.5%)	0.641
Other emergency interventions	10 (32.2%)	14 (45.1%)	0.297
Craniotomy	8 (25.8%) *	9 (29.0%)	0.753
Orthopaedic surgery	2 (6.5%)	4 (9.7%)	0.390
Other	0 (0.0%)	2 (9.7%)	0.151
Transfusion
During the first 6 h after the admission to ED
RBC (unit)	2 (0–10)	8 (2–22)	0.016
FFP (unit)	4 (0–10)	14 (4–23)	0.009
PC (unit)	0 (0–0)	0 (0–20)	0.059
From 6 to 24 h after the admission to ED
RBC (unit)	0 (0–4)	2 (0–5)	0.387
FFP (unit)	0 (0–7)	4 (0–9)	0.133
PC (unit)	0 (0–15)	0 (0–20)	0.771
FC administration during 24 h after the admission to ED	19 (61.2%)	31 (100%)	< 0.001
First FC administration after the admission to ED
0–1 h	0	31 (100%)	< 0.001
1–3 h	10 (32.2%)	0 (0.0%)
3–24 h	9 (29.0%)	0 (0.0%)
Total amounts during 24 h after the admission to ED	3 (3–3)	3 (3–3)	0.96

*A patients who has performed burr hole surgery was included
FC fibrinogen concentrate, ED emergency department, RBC red blood cell, FFP fresh frozen plasma, PC platelet concentrate

ISSN: 1749-7922