Table 2 Characteristics of studies that reported post-operative complications in comparing immediate cholecystectomy performed within 24 h from admission or within 72 h from on the onset of symptoms, compared to delayed cholecystectomy
Authors | Year | Patients | Timing | Inclusion criteria | Exclusion criteria | Pathology confirmation | Post-operative complications | P value | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
Early | Delayed | Early | Delayed | Early | Delayed | ||||||
Lai [27] | 1998 | 53 | 51 | < 24 h from admission | 6–8 weeks | Clinical Laboratory Ultrasound | CBD stone complications Previous surgery High risk for surgery Symptoms for more than 7 days | Yes | 5 | 3 | 0.8 |
Kolla [28] | 2014 | 20 | 20 | < 24 h from admission | 6–12 weeks | Clinical Laboratory Ultrasound HIDA | CBD stone complications Previous surgery High risk for surgery Symptoms for more than 96 h | No | 2 | 3 | NR |
Ozkardes [29] | 2014 | 30 | 30 | < 24 h from admission | 6–8 weeks | Clinical Laboratory Ultrasound | CBD stone complications Previous surgery High risk for surgery | No | 5 | 0 | NR |
Saber [36] | 2014 | 60 | 60 | < 72 h from symptoms | 6–8 weeks | Clinical Laboratory Ultrasound | NR | No | 6 | 4 | NR |
Jan [37] | 2016 | 50 | 50 | < 72 h from symptoms | > 72 h from symptoms Up to 7 days | Clinical Laboratory Ultrasound | CBD stone complications Previous surgery High risk for surgery Gallbladder malignancy Acalculus cholecystitis Symptoms for more than 7 days | No | 1 | 3 | NR |
Rajock [38] | 2016 | 31 | 31 | < 72 h from symptoms | 6–8 weeks | Clinical Laboratory Ultrasound | NR | Yes | 3 | 8 | NR |
Arslan Onuk [15] | 2019 | 32 | 32 | < 72 h from symptoms | > 72 h from symptoms Up to 6 days after initial treatment | Clinical Laboratory Ultrasound | CBD stone complications Previous surgery Perforation Sepsis Pregnancy Immunosuppression | Yes | 4 | 9 | 0.12 |
Arafa [39] | 2019 | 74 | 74 | < 72 h from symptoms | 6–12 weeks | Clinical Laboratory Ultrasound | CBD stone complications Previous surgery High risk for surgery Free biliary perforation Pregnancy Decompensated cirrhosis No consent available | Yes | 10 | 17 | NR |
El Kordy [40] | 2019 | 20 | 20 | < 72 h from symptoms | 6–8 weeks | Clinical Laboratory Ultrasound | NR | No | 4 | 6 | NR |