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Table 2 Arterial blood gas and biomarkers in patients with hyperoxemia and non-hyperoxemia

From: Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis

  Hyperoxemia Non-hyperoxemia P value
Arterial blood gas on arrival, median (IQR)
 PaO2, mmHg 355 (304–413) 112 (78–192) < 0.001
 FiO2 1.0 (0.8–1.0) 0.6 (0.3–1.0) < 0.001
 P/F ratio, mmHg 389 (308–481) 251 (139–391) < 0.001
 PaCO2, mmHg 40 (36–44) 38 (34–44) 0.256
Arterial blood gas at 3 h, median (IQR)
 PaO2, mmHg 205 (127–311) 104 (82–163) < 0.001
 FiO2 0.5 (0.4–0.6) 0.4 (0.2–0.5) < 0.001
 P/F ratio, mmHg 424 (321–527) 344 (229–446) < 0.001
 PaCO2, mmHg 40 (37–45) 40 (35–45) 0.517
Biomarkers on arrival, median (IQR)
 sRAGE, pg/mL 1446 (596–2786) 1046 (724–2216) 0.530
 HMGB-1, ng/mL 20.6 (11.0–46.6) 13.7 (8.7–22.1) 0.023
 SPD, ng/mL 32.0 (17.2–47.6) 30.5 (17.4–47.6) 0.952
 CCSP, ng/mL 13.6 (8.5–22.0) 9.2 (6.5–17.5) 0.086
 IL-8, pg/mL 18.2 (8.0–29.4) 11.4 (8.0–29.8) 0.230
  1. P/F PaO2/FiO2, IQR interquartile range, sRAGE soluble receptor for advanced glycation end-products, HMGB-1 high mobility group box-1, SPD surfactant protein D, CCSP Clara cell secretory protein, IL interleukin