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Table 2 Arterial blood gas and biomarkers in patients with hyperoxemia and non-hyperoxemia

From: Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis

 

Hyperoxemia

Non-hyperoxemia

P value

Arterial blood gas on arrival, median (IQR)

 PaO2, mmHg

355

(304–413)

112

(78–192)

< 0.001

 FiO2

1.0

(0.8–1.0)

0.6

(0.3–1.0)

< 0.001

 P/F ratio, mmHg

389

(308–481)

251

(139–391)

< 0.001

 PaCO2, mmHg

40

(36–44)

38

(34–44)

0.256

Arterial blood gas at 3 h, median (IQR)

 PaO2, mmHg

205

(127–311)

104

(82–163)

< 0.001

 FiO2

0.5

(0.4–0.6)

0.4

(0.2–0.5)

< 0.001

 P/F ratio, mmHg

424

(321–527)

344

(229–446)

< 0.001

 PaCO2, mmHg

40

(37–45)

40

(35–45)

0.517

Biomarkers on arrival, median (IQR)

 sRAGE, pg/mL

1446

(596–2786)

1046

(724–2216)

0.530

 HMGB-1, ng/mL

20.6

(11.0–46.6)

13.7

(8.7–22.1)

0.023

 SPD, ng/mL

32.0

(17.2–47.6)

30.5

(17.4–47.6)

0.952

 CCSP, ng/mL

13.6

(8.5–22.0)

9.2

(6.5–17.5)

0.086

 IL-8, pg/mL

18.2

(8.0–29.4)

11.4

(8.0–29.8)

0.230

  1. P/F PaO2/FiO2, IQR interquartile range, sRAGE soluble receptor for advanced glycation end-products, HMGB-1 high mobility group box-1, SPD surfactant protein D, CCSP Clara cell secretory protein, IL interleukin