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Table 1 Clinical characteristics between NF and non-NF groups

From: Utility of modified Laboratory Risk Indicator for Necrotizing Fasciitis (MLRINEC) score in distinguishing necrotizing from non-necrotizing soft tissue infections

Variable (n, % or mean ± SD)

NF group (n = 101)

Non-NF group (n = 202)

P value

Age

57.1 ± 19.8

57.0 ± 19.5

0.91

Sex (male)

67 (66.3%)

134 (66.3%)

1.0

Systolic blood pressure

103 ± 18.3

111 ± 15.1

0.53

Heart rate

98 ± 13.5

102 ± 16.7

0.32

Body temperature

36.8 ± 1.9

36.5 ± 2.3

0.84

Malignancy

7 (6.9%)

12 (5.9%)

0.87

Heart disease

15 (14.9%)

27 (13.4%)

0.75

Pulmonary disease

11 (10.9%)

23 (11.4%)

0.59

Liver disease

35 (34.7%)

30 (14.9%)

< 0.01*

Kidney disease

39 (38.6%)

25 (12.4%)

< 0.01*

Peripheral vascular disease

9 (8.9%)

12 (5.9%)

0.03*

Diabetes mellitus

36 (35.6%)

21 (10.4%)

< 0.01*

Hypertension

15 (14.9%)

28 (13.9%)

0.18

Immunosuppressants use

6 (5.9%)

10 (5.0%)

0.94

 CRP

75.6 ± 21.6

29.4 ± 19.7

< 0.01*

 CRP > 30 (mg/dL)

58 (57.4%)

49 (24.3%)

< 0.01*

 WBC

16.2 ± 6.4

11.1 ± 3.6

0.01*

 WBC > 15 (× 104 /uL)

41 (40.6%)

51 (25.2%)

< 0.01*

 Hemoglobin

10.5 ± 3.8

12.1 ± 2.9

0.04*

 Hemoglobin < 11(g/dL)

38 (37.6%)

48 (23.8%)

0.02*

 Blood glucose

168 ± 47.1

132 ± 35.8

0.02*

 Blood glucose ≧ 180(mg/dL)

29 (28.7%)

25(12.4%)

< 0.01*

 Sodium

135 ± 4.5

139 ± 3.6

0.03*

 Sodium < 135 (mEq/L)

28 (27.7%)

24 (11.9%)

0.01*

 Lactate

18.3 ± 6.5

10.6 ± 4.8

< 0.01*

 Lactate > 18 (mg/dL)

32 (31.7%)

22 (10.9%)

< 0.01*

 Creatinine

1.6 ± 0.7

1.2 ± 0.4

0.02*

 Creatinine ≧ 1.6 (mg/dL)

31 (30.7%)

24 (11.9%)

< 0.01*

  1. CRP C-reactive protein, WBC white blood cell
  2. *P < 0.05