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Table 2 The optimal cut-off value, AUC, and ROC for calculated variables

From: Utility of modified Laboratory Risk Indicator for Necrotizing Fasciitis (MLRINEC) score in distinguishing necrotizing from non-necrotizing soft tissue infections

Variable

AUC

95% CI

Lower limit

95% CI

Upper limit

P value

Cut-off value

Sensitivity

Specificity

CRP

0.863

0.803

0.927

< 0.01*

30 mg/dL

0.861

0.873

WBC

0.691

0.598

0.792

0.02*

15 × 104 /uL

0.528

0.916

Blood glucose

0.765

0.671

0.856

< 0.01*

180 mg/dL

0.692

0.758

Creatinine

0.728

0.639

0.823

< 0.01*

1.6 mg/dL

0.498

0.951

Hb

0.734

0.645

0.815

0.01*

11 g/dL

0.682

0.765

Sodium

0.667

0.591

0.827

0.02*

135 mEq/L

0.883

0.554

Lactate

0.898

0.842

0.961

< 0.01*

18 mg/dL

0.893

0.885

  1. CI confidence interval, CRP C-reactive protein, WBC white blood cell, Hb hemoglobin
  2. *P < 0.05