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Table 3 Scoring systems used for identifying complicated appendicitis

From: Periappendiceal fat-stranding models for discriminating between complicated and uncomplicated acute appendicitis: a diagnostic and validation study

Models

Variables required

Points scored

Cutoff/total points

Sensitivity (95% CI)

Specificity (95% CI)

ROC c statistics (95% CI)

1. Bröker et al. [32]

CRP

≥ 3.0 (1)

2/2

64.1% (52.3–75.8%)

83.1% (79.1–87.1%)

0.778 (0.719–0.837)

 

Duration of symptoms

≥ 2 days (1)

    

2. Imaoka et al. [28]

Temp

≥ 37.4 °C (1)

1/3

84.9% (77.4–94.5%)

68.6% (63.7–73.6%)

0.800 (0.745–0.854)

 

CRP

≥ 4.7 (1)

    
 

Periappendiceal fluid

Yes (1)

    

3. Khan et al. [16]

Age

40–59 years (1)

2/4

73.4% (62.6–84.3%)

58.8% (53.6–61.1%)

0.694 (0.630–0.759)

  

≥ 60 years (2)

    
 

Duration of symptoms

≥ 2 days (1)

    
 

Appendicolith

Yes (1)

    

4. TH Kim et al. [33]

Appendiceal diameter

> 10 mm (1)

3/4

56.3% (44.1–68.4%)

86.1% (82.4–89.8%)

0.777 (0.718–0.835)

 

Ascites

Yes (1)

    
 

Fat stranding

Yes (1)

    
 

CRP

> 5.0 mg/dL (1)

    

5. Kang et al. [34]

Temp

≥ 37.9 °C (1)

4/8

60.9% (49.0–72.9%)

85.2% (81.4–89.0%)

0.772 (0.706–0.839)

 

Abdominal pain score

4–6 (1), ≥ 7 (2)

    
 

WBC count

> 13,660/μL (1)

    
 

NLR

≥ 10.9 (1)

    
 

CRP

≥ 6.6 (3)

    

6. Atema et al. [31]

Age

≥ 45 years (2)

7/22

76.6% (66.2–86.9%)

74.8% (70.2–79.5%)

0.826 (0.774–0.878)

 

Temp

≤ 37.0 °C (0)

    
  

37.1–37.9 °C (2)

    
  

≥ 38.0 °C (4)

    
 

Duration of symptoms

≥ 48 h (2)

    
 

WBC count

> 13,000/μL (2)

    
 

CRP (mg/dL)

≤ 5.0 (0)

    
  

5.0–10.0 (1)

    
  

> 10.0 (2)

    
 

Extraluminal free air

Present (5)

    
 

Periappendiceal fluid

Present (2)

    
 

Appendicolith

Present (2)

    

7. Avanesov et al. [36]

Age

≥ 52 years (1)

2/10

81.3% (71.7–90.8%)

69.2% (64.3–74.2%)

0.806 (0.749–0.862)

 

Temp

≥ 37.5 °C (1)

    
 

Duration of symptoms

≥ 48 h (1)

    
 

Appendix diameter

≥ 14 mm (1)

    
 

Periappendiceal fluid

Present (2)

    
 

Extraluminal air present

Present (1)

    
 

Abscess

Present (3)

    

8. HY Kim et al. [37]

Segmented neutrophils

≥ 81% (1)

3/6

64.1% (52.3–75.8%)

87.6% (84.1–91.0%)

0.838 (0.788–0.889)

 

Contrast-enhancement of the appendiceal wall

Defect (1)

    
 

Abscess

Present (1)

    
 

Fat stranding

Moderate or severe (1)

    
 

Appendiceal diameter

≥ 10 mm (1)

    
 

Extraluminal air

Present (1)

    

9. Model 1 (our model)

CRP (mg/dL)

3.0–5.9 (2)

6/10

82.8% (73.6–92.1%)

82.8% (78.5–86.6%)

0.878 (0.829–0.928)

  

≥ 6.0 mg/dL (3)

    
 

Fat stranding

Grade 1 (3)

    
  

Grade 2 (4)

    
  

Grade 3 (5)

    
 

Appendicolith

Present (1)

    
 

Ascites

Present (1)

    

10. Model 2 (our model)

CRP (mg/dL)

3.0–5.9 (2)

6/10

81.3% (71.7–90.8%)

82.3% (78.2–86.3%)

0.879 (0.830–0.927)

  

≥ 6.0 mg/dL (3)

    
 

Fat stranding

Grade 1 (3)

    
  

Grade 2 (4)

    
  

Grade 3 (5)

    
 

NLR

> 10 (1)

    
 

Ascites

Present (1)

    
  1. CRP C-reactive protein, CRP C-reactive protein, CT computed tomography, NLR neutrophil to lymphocyte ratio, WBC white blood cell