Table 2 Mean clinical parameters on admission
Variable | Total cohort n = 649 (%) | Severe bleed n = 226 (%) | Non-severe bleed n = 423 (%) | P value |
|---|---|---|---|---|
HR (SD) | 83 (16) | 86 (17) | 81 (15) | 0.009 |
≥ 100 | 91 (14.0) | 51 (22.6) | 40 (9.5) | |
< 100 | 558 (86.0) | 175 (77.4) | 383 (90.5) | < 0.001 |
SBP, mmHg (SD) | 134.8 (25.3) | 126 (27) | 140 (23) | 0.002 |
< 90 | 16 (2.5) | 14 (6.2) | 2 (0.5) | |
≥ 90 | 633 (97.5) | 212 (93.8) | 421 (99.5) | < 0.001 |
DBP, mmHg (SD) | 72 (13) | 66 (13) | 75 (12) | 0.001 |
MAP, mmHg (SD) | 93 (16) | 86 (16) | 96 (14) | 0.48 |
< 65 | 14 (2.2) | 11 (4.9) | 3 (0.7) | |
≥ 65 | 632 (97.4) | 212 (93.8) | 420 (99.3) | 0.001 |
Hb, g/dL (SD) | 11.3 (2.8) | 9.1 (2.6) | 12.5 (2.1) | < 0.001 |
< 9 | 127 (19.6) | 106 (46.9) | 21 (5.0) | |
≥ 9 | 521 (80.3) | 120 (53.1) | 401 (94.8) | < 0.001 |
Hct, % (SD) | 34.4 (7.7) | 28.5 (7.4) | 37.6 (5.8) | < 0.001 |
> 35 | 344 (53.0) | 46 (20.4) | 298 (70.4) | |
≤ 35 | 304 (46.8) | 180 (79.6) | 124 (29.3) | < 0.001 |
AKI | 216 (33.3) | 102 (45.1) | 114 (27.0) | < 0.001 |
Coagulopathy, INR ≥ 1.5 | 27 (4.2) | 14 (6.2) | 13 (3.1) | 0.08 |
HCO3, mEq/L (SD) | 23.9 (3.0) | 22.8 (3.3) | 24.5 (2.6) | 0.003 |
≤ 19 | 45 (6.9) | 29 (12.8) | 16 (3.8) | |
> 19 | 594 (91.5) | 193 (85.4) | 401 (94.8) | < 0.001 |
Active PR bleed | 227 (35.0) | 99 (43.8) | 128 (30.3) | 0.001 |
Cardiovascular collapse | 2 (0.3) | 2 (0.9) | 0 (0) | 0.12 |