Study | Amounts of RBCs (Units) | Amounts of plasma (Units) | Amounts of platelets (Units) | Amounts of cryoprecipitate/fibrinogen (Units) | Main findings |
---|---|---|---|---|---|
VHA group versus Control group | VHA group versus Control group | VHA group versus Control group | VHA group versus Control group | ||
Baksaas-Aasen [29] | 6 (3–10) versus 6 (4–6) | 6 (3–10) versus 7 (4–11) a* | 2 (1–3) versus 1 (0–2) pools b* | 4 (0–4) versus 3 (0–4) g c | Patients in the VHA group received more platelet, and less plasma at 24 h after injury, no statistically differences in the amounts of RBCs and fibrinogen equivalent were found between the two groups Patients in the VHA group received more platelet, and fibrinogen equivalent between the baseline and hemostasis, no statistically differences in the amounts of RBCs and plasma were found between the two groups |
Cochrane [20] | 3.9 ± 4.0 versus 3.6 ± 3.3 | 2.6 ± 3.8 versus 2.5 ± 3.4 a | 0.4 ± 0.8 versus 0.2 ± 0.5 | 0. 5 ± 1.1 versus 0.3 ± 1.0 d | No statistical differences in the number of blood components were found between the two groups, although there was a trend for more use of platelets in the post-TEG group |
Campbell [21] | 5.36 ± 5.50 versus 4.57 ± 3.77 | 0 ± 0.97 versus 2.19 ± 3.17 *** | 0.51 ± 1.11 versus 0.30 ± 0.77 | 0.73 ± 1.68 versus 0 ± 0 g e *** 9.17 ± 14.83 versus 1.35 ± 3.46 d*** | RBCs amounts did not significantly change There was a significant increase in cryoprecipitate and fibrinogen in the post-ROTEM group, accompanied by a reduction in the use of plasma and prothrombinex Platelet usage was higher in the post-ROTEM group but did not reach statistical significance |
Unruh [22] | 6 (3–10) versus 11 (8–13) *** | 4.5 (2–7.5) versus 4 (3–8.5) | 1.5 (1–3) versus 2 (1–2) | 1 (1–1) versus 2 (1-n/a) d | ITT analysis demonstrated a significant reduction in the amounts of RBCs transfusions, the number of patients receiving plasma and platelets in the post-TEG group |
Wang [23] | 4 ± 7 versus 9 ± 10 ** | 1 ± 5 versus 5 ± 6 ** | 0.4 ± 1.5 versus 2.9 ± 4.8 ** | 0.1 ± 0.5 versus 0.3 ± 1.2 d | Patients in the TEG group received fewer amounts of RBCs, plasma, and platelets |
Mohamed [24] | 4.09 versus 7.69 ** | 4.30 versus 6.43 * | 2.28 versus 0.83 * | 0.38 versus 0.47 d | Over 24Â h, all patients in the post-TEG group had less RBCs and plasma, and more platelets In the first 4Â h, all patients in the post-TEG group had more plasma and platelets, and similar RBCs |
Gonzalez [28] | 9.5 (5–16) versus 11 (6–16) | 5.0 (3–9) versus 6.0 (4–9) | 1.0 (0–2) versus 1.0 (0–2) | 0.0 (0–2) versus 1.0 (0–2) d* | Less cryoprecipitate was used cumulatively at 24 h in the TEG group TEG group patients received less plasma, and platelets in the first 2 h of resuscitation |
Yin [25] | 5 (3–13) versus 6.5 (4–14) | 5.7 (3.4–10) versus 6.1 (4–10.7) | 0 (0–0) versus 0 (0–10) | 0 (0–5) versus 0 (0–10) d | No statistical differences in the amounts of blood components were found between the two groups Subgroup analysis including patients with ISS ≥ 16 showed that patients in the post-TEG group had significantly fewer consumption of RBCs, plasma, and total blood products |
Tapia [26] | – | – | – | – | For patients receiving 6U or more RBCs, there was no difference in amounts of blood components between the TEG-guided group and MTP group Blunt MOI patients who received 10U or more RBCs in the TEG-guided group received less plasma |
Kashuk [27] | – | – | – | – | Although there was a trend for fewer products in the post-TEG group, there were no significant differences |