Table 1 Characteristics of bleeding among treatment groups

Experiment 1

Liver biopsy (n)

40

40

40

40

40

N/A

Blood flow (ml/min)*

8.2 (3.5)

8.2 (3.2)

7.4 (2.0)

7.9 (2.4)

7.8 (2.5)

N/A

Mean arterial pressure (mm Hg)

55.5 (11.7)

54.0 (11.7)

52.6 (7.6)

54.3 (11.8)

53.9 (12.3)

N/A

Spleen biopsy (n)

20

20

20

20

20

N/A

Blood flow (ml/min)*

7.7 (1.7)

6.9 (1.6)

6.8 (1.1)

7.4 (1.8)

6.9 (1.0)

N/A

Mean arterial pressure (mm Hg)

53.8 (11.9)

53.4 (12.0)

52.8 (10.3)

51.2 (6.9)

54.8 (11.6)

N/A

Experiment 2 Non-heparinized pigs

Liver resections (n)

7

8

6

7

N/A

8

Spleen resections (n)

8

6

8

7

N/A

7

Mean arterial pressure (mm Hg)

49.0 (3.0)

46.7 (7.1)

47.4 (5.7)

37.2 (11.5)

N/A

46.1 (6.4)

ACT baseline (s)

98

90

98

86

N/A

102

ACT during experiment (s)

98

90

89

87

N/A

98

Experiment 2 Heparinized pigs

Liver resections (n)

5

6

5

5

N/A

7

Spleen resections (n)

8

4

8

6

N/A

6

Mean arterial pressure (mm Hg)

49.9 (13.4)

42.4 (6.1)

56.7 (6.5)

46.0 (9.0)

N/A

50.4 (7.5)

ACT baseline (s)

92

87

92

98

N/A

101

ACT during experiment (s)

222

315

208

194

N/A

235