Articles

The impact of polytrauma on sRAGE levels: evidence and statistical analysis of temporal variations

According to recently published findings, levels of the soluble receptor of advanced glycation end products (sRAGE) and its clearance from the blood may reflect the evolution of lung damage during hospitalizat...

Authors: Lukas L. Negrin, Robin Ristl, Gabriel Halat, Thomas Heinz and Stefan Hajdu

Intra-operative gallbladder scoring predicts conversion of laparoscopic to open cholecystectomy: a WSES prospective collaborative study

Laparoscopic cholecystectomy, the gold-standard approach for cholecystectomy, has surprisingly variable outcomes and conversion rates. Only recently has operative grading been reported to define disease severi...

Authors: Michael Sugrue, Federico Coccolini, Magda Bucholc and Alison Johnston

Development and validation of a novel predictive score for sepsis risk among trauma patients

Patients suffering from major trauma often experience complications such as sepsis. The early recognition of patients at high risk of sepsis after trauma is critical for precision therapy. We aimed to derive a...

Authors: Hong-xiang Lu, Juan Du, Da-lin Wen, Jian-hui Sun, Min-jia Chen, An-qiang Zhang and Jian-xin Jiang

2017 WSES and SICG guidelines on acute calcolous cholecystitis in elderly population

Gallstone disease is very common afflicting 20 million people in the USA. In Europe, the overall incidence of gallstone disease is 18.8% in women and 9.5% in men. The frequency of gallstones related disease in...

Authors: Michele Pisano, Marco Ceresoli, Stefania Cimbanassi, Kurinchi Gurusamy, Federico Coccolini, Giuseppe Borzellino, Gianluca Costa, Niccolò Allievi, Bruno Amato, Djamila Boerma, Pietro Calcagno, Luca Campanati, Fabio Cesare Campanile, Alberto Casati, Osvaldo Chiara, Antonio Crucitti…

Preserve encephalus in surgery of trauma: online survey. (P.E.S.T.O)

Traumatic brain injury (TBI) is a global health problem. Extracranial hemorrhagic lesions needing emergency surgery adversely affect the outcome of TBI. We conducted an international survey regarding the acute...

Authors: Edoardo Picetti, Ronald V. Maier, Sandra Rossi, Andrew W. Kirkpatrick, Walter L. Biffl, Philip F. Stahel, Ernest E. Moore, Yoram Kluger, Gian Luca Baiocchi, Luca Ansaloni, Vanni Agnoletti and Fausto Catena

2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients

In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical pa...

Authors: Massimo Sartelli, Stefano Di Bella, Lynne V. McFarland, Sahil Khanna, Luis Furuya-Kanamori, Nadir Abuzeid, Fikri M. Abu-Zidan, Luca Ansaloni, Goran Augustin, Miklosh Bala, Offir Ben-Ishay, Walter L. Biffl, Stephen M. Brecher, Adrián Camacho-Ortiz, Miguel A. Caínzos, Shirley Chan…

Open conversion for laparoscopically difficult cholecystectomy is still a valid solution with unsolved aspects

The difficult laparoscopic cholecystectomy remains a surgical challenge for surgeons who must decide between laparoscopic continuation and open conversion. The balance between the lack of open surgery training...

Authors: M. Mannino, A. Toro, M. Teodoro, F. Coccolini, M. Sartelli, L. Ansaloni, F. Catena and I. Di Carlo

Pre-hospital plasma in haemorrhagic shock management: current opinion and meta-analysis of randomized trials

Trauma-induced coagulopathy is one of the most difficult issues to manage in severely injured patients. The plasma efficacy in treating haemorrhagic-shocked patients is well known. The debated issue is the tim...

Authors: Federico Coccolini, Giacinto Pizzilli, Davide Corbella, Massimo Sartelli, Vanni Agnoletti, Vanessa Agostini, Gian Luca Baiocchi, Luca Ansaloni and Fausto Catena

Medications and patient safety in the trauma setting: a systematic review

Medication errors account for the most common adverse events and a significant cause of mortality in the USA. The Joint Commission has required medication reconciliation since 2006. We aimed to survey the lite...

Authors: Jonathan H. DeAntonio, Tammy Nguyen, Gregory Chenault, Michel B. Aboutanos, Rahul J. Anand, Paula Ferrada, Stephanie Goldberg, Stefan W. Leichtle, Levi D. Procter, Edgar B. Rodas, Alan P. Rossi, James F. Whelan, V. Ramana Feeser, Michael J. Vitto, Beth Broering, Sarah Hobgood…

Feasibility of ultrasound measurement in a human model of acute compartment syndrome

Early diagnosis of acute compartment syndrome (ACS) of the leg is essential to improve the outcome. Direct invasive measurement is currently recommended to measure intracompartmental pressure. A non-invasive a...

Authors: Jakob Mühlbacher, Reinhard Pauzenberger, Ulrika Asenbaum, Tobias Gauster, Stephan Kapral, Harald Herkner and Andreas Duma

Transcatheter arterial embolization versus surgery for refractory non-variceal upper gastrointestinal bleeding: a meta-analysis

Nowadays, very few patients with non-variceal upper gastrointestinal bleeding fail endoscopic hemostasis (refractory NVUGIB). This subset of patients poses a clinical dilemma: should they be operated on or ref...

Authors: Antonio Tarasconi, Gian Luca Baiocchi, Vittoria Pattonieri, Gennaro Perrone, Hariscine Keng Abongwa, Sarah Molfino, Nazario Portolani, Massimo Sartelli, Salomone Di Saverio, Arianna Heyer, Luca Ansaloni, Federico Coccolini and Fausto Catena

Is early appendectomy in adults diagnosed with acute appendicitis mandatory? A prospective study

Prompt appendectomy has long been the standard of care for acute appendicitis in order to prevent complications such as perforation, abscess formation, and diffuse purulent or fecal peritonitis, all resulting ...

Authors: Salma Abu Foul, Ella Egozi, Ahmad Assalia, Yoram Kluger and Ahmad Mahajna

Kunafa knife and play dough is an efficient and cheap simulator to teach diagnostic Point-of-Care Ultrasound (POCUS)

Point-of-Care Ultrasound (POCUS) is a useful diagnostic tool. Nevertheless, it needs proper training to reach its required level of competency. Educators who work in low-income countries find it difficult to p...

Authors: Fikri M. Abu-Zidan and Arif Alper Cevik

2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to...

Authors: Massimo Sartelli, Xavier Guirao, Timothy C. Hardcastle, Yoram Kluger, Marja. A. Boermeester, Kemal Raşa, Luca Ansaloni, Federico Coccolini, Philippe Montravers, Fikri M. Abu-Zidan, Michele Bartoletti, Matteo Bassetti, Offir Ben-Ishay, Walter L. Biffl, Osvaldo Chiara, Massimo Chiarugi…

Predictors of Change in Functional Outcome at six months and twelve months after Severe Injury: A Retrospective Cohort Study

There is increasing focus on long-term survival, function and quality-of-life for trauma patients. There are few studies tracking longitudinal changes in functional outcome over time. The goal of our study was...

Authors: Aidan Lyanzhiang Tan, Yi Chiong, Nivedita Nadkarni, Jolene Yu Xuan Cheng, Ming Terk Chiu and Ting Hway Wong

First clinical experiences of concurrent bleeding control and intracranial pressure monitoring using a hybrid emergency room system in patients with multiple injuries

The outcomes of multiple injury patients with concomitant torso hemorrhage and traumatic brain injury (TBI) are very poor. The hybrid emergency room system (HERS) is a trauma management system designed to comp...

Authors: Takahiro Kinoshita, Kazuma Yamakawa, Jumpei Yoshimura, Atsushi Watanabe, Yosuke Matsumura, Kaori Ito, Hiroyuki Ohbe, Kei Hayashida, Shigeki Kushimoto, Junichi Matsumoto and Satoshi Fujimi

Outcomes of selective nonoperative management of civilian abdominal gunshot wounds: a systematic review and meta-analysis

Although mandatory laparotomy has been standard of care for patients with abdominal gunshot wounds (GSWs) for decades, this approach is associated with non-therapeutic operations, morbidity, and long hospital ...

Authors: Aziza N. Al Rawahi, Fatma A. Al Hinai, Jamie M. Boyd, Christopher J. Doig, Chad G. Ball, George C. Velmahos, Andrew W. Kirkpatrick, Pradeep H. Navsaria and Derek J. Roberts

Three cases of resuscitative endovascular balloon occlusion of the aorta (REBOA) in austere pre-hospital environment—technical and methodological aspects

The present paper describes three cases where ER-REBOA® was used with partial aorta occlusion (AO), by performing a partial resuscitative endovascular balloon occlusion of the aorta or pREBOA, in an austere pr...

Authors: J. C. de Schoutheete, I. Fourneau, F. Waroquier, L. De Cupere, M. O’Connor, K. Van Cleynenbreugel, J. C. Ceccaldi and S. Nijs

Vacuum-assisted closure (VAC®) systems and microbiological isolation of infected wounds

Negative pressure wound therapy is now largely used to treat infected wounds. The prevention and reduction of healthcare-associated infections is a high priority for any Department of Health and great efforts ...

Authors: Valerio Cozza, Gilda Pepe, Marco Cintoni, Flavio De Maio, Giuseppe Tropeano, Sabina Magalini, Gabriele Sganga, Giovanni Delogu and Daniele Gui

LBP rs2232618 polymorphism contributes to risk of sepsis after trauma

Previous study revealed that rs2232618 polymorphism (Phe436Leu) within LBP gene is a functional variant and associated with susceptibility of sepsis in traumatic patients. Our aim was to confirm the reported a...

Authors: Hong-xiang Lu, Jian-hui Sun, Da-lin Wen, Juan Du, Ling Zeng, An-qiang Zhang and Jian-xin Jiang

Multi-organ protection of ulinastatin in traumatic cardiac arrest model

Post-cardiac arrest syndrome, which has no specific curative treatment, contributes to the high mortality rate of victims who suffer traumatic cardiac arrest (TCA) and initially can be resuscitated. In the pre...

Authors: Shaoyun Liu, Jiefeng Xu, Yuzhi Gao, Peng Shen, Senlin Xia, Zilong Li and Mao Zhang

Abdominopelvic trauma: from anatomical to anatomo-physiological classification

Abdominopelvic trauma has been for decades classified with the AAST-OIS (American Association for the Surgery of Trauma—Organ Injury Scale) classification. It has represented a milestone. At present, the medic...

Authors: Federico Coccolini, Fausto Catena, Yoram Kluger, Massimo Sartelli, Gianluca Baiocchi, Luca Ansaloni and Ernest Eugene Moore

Effect of resuscitative endovascular balloon occlusion of the aorta in hemodynamically unstable patients with multiple severe torso trauma: a retrospective study

Although resuscitative endovascular balloon occlusion of the aorta (REBOA) may be effective in trauma management, its effect in patients with severe multiple torso trauma remains unclear.

Authors: Hiroyuki Otsuka, Toshiki Sato, Keiji Sakurai, Hiromichi Aoki, Takeshi Yamagiwa, Shinichi Iizuka and Sadaki Inokuchi

Small bowel obstruction in the elderly: a plea for comprehensive acute geriatric care

Small bowel obstruction is one of the most frequent emergencies in general surgery, commonly affecting elderly patients. Morbidity and mortality from small bowel obstruction in elderly is high. Significant pro...

Authors: Ekin Ozturk, Marianne van Iersel, Martijn MWJ Stommel, Yvonne Schoon, Richard RPG ten Broek and Harry van Goor

Diagnostic point-of-care ultrasound (POCUS) for gastrointestinal pathology: state of the art from basics to advanced

The use of point-of-care ultrasound (POCUS) by non-radiologists has dramatically increased. POCUS is completely different from the routine radiological studies. POCUS is a Physiological, On spot, extension of ...

Authors: Fikri M Abu-Zidan and Arif Alper Cevik

A tribute to Ernest E. “Gene” Moore

Authors: Jeffry Kashuk, Walter Biffl, Yoram Kluger, Luca Ansaloni and Fausto Catena

Risk factors for mortality in the late amputation of necrotizing fasciitis: a retrospective study

Necrotizing fasciitis (NF) is a rapidly progressive infectious disease that primarily involves the fascia and subcutaneous tissue. If not promptly treated, it can lead to morbidity as well as mortality. It can...

Authors: Chia-Peng Chang, Cheng-Ting Hsiao, Chun-Nan Lin and Wen-Chih Fann

Resuscitative endovascular balloon occlusion of the aorta deployed by acute care surgeons in patients with morbidly adherent placenta: a feasible solution for two lives in peril

Morbidly adherent placenta (MAP), which includes accreta, increta, and percreta, is a condition characterized by the invasion of the uterine wall by placental tissue. The condition is associated with higher od...

Authors: Ramiro Manzano-Nunez, Maria F. Escobar-Vidarte, Claudia P. Orlas, Juan P. Herrera-Escobar, Samuel M. Galvagno, Juan J. Melendez, Natalia Padilla, Justin C. McCarty, Albaro J. Nieto and Carlos A. Ordoñez

Impact of initial temporary abdominal closure in damage control surgery: a retrospective analysis

Damage control surgery has revolutionized trauma surgery. Use of damage control surgery allows for resuscitation and reversal of coagulopathy at the risk of loss of abdominal domain and intra-abdominal complic...

Authors: Parker Hu, Rindi Uhlich, Frank Gleason, Jeffrey Kerby and Patrick Bosarge

Flexible versus rigid endoscopy in the management of esophageal foreign body impaction: systematic review and meta-analysis

Foreign body (FB) impaction accounts for 4% of emergency endoscopies in clinical practice. Flexible endoscopy (FE) is recommended as the first-line therapeutic option because it can be performed under sedation...

Authors: Davide Ferrari, Alberto Aiolfi, Gianluca Bonitta, Carlo Galdino Riva, Emanuele Rausa, Stefano Siboni, Francesco Toti and Luigi Bonavina

A combination of SOFA score and biomarkers gives a better prediction of septic AKI and in-hospital mortality in critically ill surgical patients: a pilot study

Sepsis is a syndrome characterized by a constellation of clinical manifestations and a significantly high mortality rate in the surgical intensive care unit (ICU). It is frequently complicated by acute kidney ...

Authors: Chao-Wei Lee, Hao-wei Kou, Hong-Shiue Chou, Hsu-huan Chou, Song-Fong Huang, Chih-Hsiang Chang, Chun-Hsing Wu, Ming-Chin Yu and Hsin-I Tsai

Implementation and adoption of advanced care planning in the elderly trauma patient

Geriatric trauma has high morbidity and mortality, often requiring extensive hospital stays and interventions. The number of geriatric trauma patients is also increasing significantly and accounts for a large ...

Authors: K. Verhoeff, P. Glen, A. Taheri, B. Min, B. Tsang, V. Fawcett and S. Widder

The long-term outcomes of early abdominal wall reconstruction by bilateral anterior rectus abdominis sheath turnover flap method in critically ill patients requiring open abdomen

In a previous study, we reported the usefulness of early abdominal wall reconstruction using bilateral anterior rectus abdominis sheath turnover flap method (turnover flap method) in open abdomen (OA) patients...

Authors: Masatoku Arai, Shiei Kim, Hiromoto Ishii, Jun Hagiwara, Shigeki Kushimoto and Hiroyuki Yokota

Introduction of a mass burn casualty triage system in a hospital during a powder explosion disaster: a retrospective cohort study

The triage system used during an actual mass burn casualty (MBC) incident is a major focus of concern. This study introduces a MBC triage system that was used by a burn center during an actual MBC incident fol...

Authors: Chip-Jin Ng, Shih-Hao You, I-Lin Wu, Yi-Ming Weng, Chung-Hsien Chaou, Cheng-Yu Chien and Chen-June Seak

Knowledge, awareness, and attitude towards infection prevention and management among surgeons: identifying the surgeon champion

Despite evidence supporting the effectiveness of best practices of infection prevention and management, many surgeons worldwide fail to implement them. Evidence-based practices tend to be underused in routine ...

Authors: Massimo Sartelli, Yoram Kluger, Luca Ansaloni, Federico Coccolini, Gian Luca Baiocchi, Timothy C. Hardcastle, Ernest E. Moore, Addison K. May, Kamal M. F. Itani, Donald E. Fry, Marja A. Boermeester, Xavier Guirao, Lena Napolitano, Robert G. Sawyer, Kemal Rasa, Fikri M. Abu-Zidan…

2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation

Obstruction and perforation due to colorectal cancer represent challenging matters in terms of diagnosis, life-saving strategies, obstruction resolution and oncologic challenge. The aims of the current paper a...

Authors: Michele Pisano, Luigi Zorcolo, Cecilia Merli, Stefania Cimbanassi, Elia Poiasina, Marco Ceresoli, Ferdinando Agresta, Niccolò Allievi, Giovanni Bellanova, Federico Coccolini, Claudio Coy, Paola Fugazzola, Carlos Augusto Martinez, Giulia Montori, Ciro Paolillo, Thiago Josè Penachim…

The abdominal wall hernia in cirrhotic patients: a historical challenge

The incidence rate of abdominal wall hernia is 20–40% in cirrhotic patients. A surgical approach was originally performed only if complication signs and symptoms occurred. Several recent studies have demonstra...

Authors: Giuseppe Salamone, Leo Licari, Giovanni Guercio, Sofia Campanella, Nicolò Falco, Gregorio Scerrino, Sebastiano Bonventre, Girolamo Geraci, Gianfranco Cocorullo and Gaspare Gulotta

Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery: a brief radiological commentary

The aim of this letter is to report some deeper explanations regarding the role of imaging in acute mesenteric ischemia.

Authors: Maria Antonietta Mazzei

Correlation between modified LEMON score and intubation difficulty in adult trauma patients undergoing emergency surgery

Prediction of difficult airway is critical in the airway management of trauma patients. A LEMON method which consists of following assessments; Look-Evaluate-Mallampati-Obstruction-Neck mobility is a fast and eas...

Authors: Sung-Mi Ji, Eun-Jin Moon, Tae-Jun Kim, Jae-Woo Yi, Hyungseok Seo and Bong-Jae Lee

Acute care and emergency general surgery in patients with chronic liver disease: how can we optimize perioperative care? A review of the literature

The increasing prevalence of advanced cirrhosis among operative candidates poses a major challenge for the acute care surgeon. The severity of hepatic dysfunction, degree of portal hypertension, emergency of s...

Authors: Michael S. Bleszynski, Alexsander K. Bressan, Emilie Joos, S. Morad Hameed and Chad G. Ball

Ischemic colitis caused increased early and delayed mortality

Ischemic colitis remains a challenge for the surgeon, both in its diagnosis and treatment. Data from a single tertiary center, of patients diagnosed with ischemic colitis, was collected. An attempt was made to...

Authors: Hayim Gilshtein, Kenan Hallon and Yoram Kluger

Blunt cerebrovascular injury in elderly fall patients: are we screening enough?

Blunt cerebrovascular injuries (BCVI) are generally associated with high-energy injury mechanisms. Less is known regarding lower-energy injuries in elderly patients. We sought to determine the incidence of BCV...

Authors: Vincent P. Anto, Joshua B. Brown, Andrew B. Peitzman, Brian S. Zuckerbraun, Matthew D. Neal, Gregory Watson, Raquel Forsythe, Timothy R. Billiar and Jason L. Sperry

ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery

Postoperative complications and delayed physical recovery are significant problems following emergency abdominal surgery. Physiotherapy aims to aid recovery and prevent complications in the acute phase after s...

Authors: Ianthe Boden, Kate Sullivan, Claire Hackett, Brooke Winzer, Rebecca Lane, Melissa McKinnon and Iain Robertson

Should ambulatory appendectomy become the standard treatment for acute appendicitis?

Appendectomy is increasingly performed as a ‘short stay’ or ‘ambulatory’ procedure, yet there is no consensus for selection of patients with acute appendicitis for ambulatory surgery (AS). We aimed to compare ...

Authors: Benoit Gignoux, Marie-Cecile Blanchet, Thomas Lanz, Alexandre Vulliez, Mo Saffarini, Hugo Bothorel, Maud Robert and Vincent Frering

Emergency surgeons’ perceptions and attitudes towards antibiotic prescribing and resistance: a worldwide cross-sectional survey

Antibiotic resistance (AMR) is a growing public health problem worldwide, in part related to inadequate antibiotic use. A better knowledge of physicians’ motivations, attitudes and practice about AMR and presc...

Authors: Francesco M. Labricciosa, Massimo Sartelli, Sofia Correia, Lilian M. Abbo, Milton Severo, Luca Ansaloni, Federico Coccolini, Carlos Alves, Renato Bessa Melo, Gian Luca Baiocchi, José-Artur Paiva, Fausto Catena and Ana Azevedo

Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial

Severe complicated intra-abdominal sepsis (SCIAS) has an increasing incidence with mortality rates over 80% in some settings. Mortality typically results from disruption of the gastrointestinal tract, progress...

Authors: Andrew W. Kirkpatrick, Federico Coccolini, Luca Ansaloni, Derek J. Roberts, Matti Tolonen, Jessica L. McKee, Ari Leppaniemi, Peter Faris, Christopher J. Doig, Fausto Catena, Timothy Fabian, Craig N. Jenne, Osvaldo Chiara, Paul Kubes, Braden Manns, Yoram Kluger…

A contemporary case series of Fournier’s gangrene at a Swiss tertiary care center—can scoring systems accurately predict mortality and morbidity?

Fournier’s gangrene (FG) is a life-threatening infection of the genital, perineal, and perianal regions with a morbidity range between 3 and 67%. Our aim is to report our experience in treatment of FG and to a...

Authors: C. Wetterauer, J. Ebbing, A. Halla, R. Kuehl, S. Erb, A. Egli, D. J. Schaefer and H. H. Seifert

Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

Adhesive small bowel obstruction (ASBO) is a common surgical emergency, causing high morbidity and even some mortality. The adhesions causing such bowel obstructions are typically the footprints of previous ab...

Authors: Richard P. G. ten Broek, Pepijn Krielen, Salomone Di Saverio, Federico Coccolini, Walter L. Biffl, Luca Ansaloni, George C. Velmahos, Massimo Sartelli, Gustavo P. Fraga, Michael D. Kelly, Frederick A. Moore, Andrew B. Peitzman, Ari Leppaniemi, Ernest E. Moore, Johannes Jeekel, Yoram Kluger…

Clinical prediction score for superficial surgical site infection after appendectomy in adults with complicated appendicitis

Superficial surgical site infection (SSI) is common after appendectomy. This study aims to determine a clinical prediction score for SSI after appendectomy in complicated appendicitis.

Authors: Pinit Noorit, Boonying Siribumrungwong and Ammarin Thakkinstian

Stump appendicitis: a retrospective review of 3130 consecutive appendectomy cases

Stump appendicitis is inflammation of remnant appendix tissue due to incomplete removal of the appendix. Due to appendectomy history, stump appendicitis diagnosis is usually delay and that can cause increase m...

Authors: Enis Dikicier, Fatih Altintoprak, Kayhan Ozdemir, Kemal Gundogdu, Mustafa Yener Uzunoglu, Guner Cakmak, Feyyaz Onuray and Recai Capoglu