Articles

Pregnancy and appendicitis: a systematic review and meta-analysis on the clinical use of MRI in diagnosis of appendicitis in pregnant women

The aim of this systematic review and meta-analysis was to evaluate the clinical use of MRI for the evaluation of acute appendicitis during pregnancy.

Authors: Mania Kave, Fateme Parooie and Morteza Salarzaei

IL-33 and its increased serum levels as an alarmin for imminent pulmonary complications in polytraumatized patients

According to recently published findings, we hypothesized that serum interleukin-33 (IL-33) may qualify for predicting pulmonary complications in polytraumatized patients.

Authors: Gabriel Halát, Thomas Haider, Michel Dedeyan, Thomas Heinz, Stefan Hajdu and Lukas L. Negrin

Does the conventional landmark help to place the tip of REBOA catheter in the optimal position? A non-controlled comparison study

Resuscitative endovascular balloon occlusion of the aorta (REBOA) for patients with traumatic torso hemorrhagic shock is available to keep a minimum level of circulatory status as a bridge to definitive therap...

Authors: Kento Nakajima, Hayato Taniguchi, Takeru Abe, Keishi Yamaguchi, Tomoki Doi, Ichiro Takeuchi and Naoto Morimura

Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study

Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to...

Authors: Massimo Sartelli, Fikri M. Abu-Zidan, Francesco M. Labricciosa, Yoram Kluger, Federico Coccolini, Luca Ansaloni, Ari Leppäniemi, Andrew W. Kirkpatrick, Matti Tolonen, Cristian Tranà, Jean-Marc Regimbeau, Timothy Hardcastle, Renol M. Koshy, Ashraf Abbas, Ulaş Aday, A. R. K. Adesunkanmi…

Diagnosis of abdominal tuberculosis: lessons learned over 30 years: pectoral assay

Diagnosing abdominal tuberculosis remains a great challenge even for experienced clinicians. It is a great mimicker that has unusual presentations. A high index of suspicion is essential for reaching its diagn...

Authors: Fikri M. Abu-Zidan and Mohamud Sheek-Hussein

Primary resection anastomosis versus Hartmann’s procedure in Hinchey III and IV diverticulitis

Surgical management of Hinchey III and IV diverticulitis utilizes either Hartmann’s procedure (HP) or primary resection anastomosis (PRA) with or without fecal diversion. The aim of this meta-analysis is to de...

Authors: Hosam Halim, Alan Askari, Rebecca Nunn and James Hollingshead

Determinants of treatment and outcomes of diverticular abscesses

Diverticular abscess diameter of 3–6 cm is generally accepted as a cutoff determining whether percutaneous drainage is recommended in addition to antibiotics, but this is not based on high-quality evidence. Th...

Authors: Juha Mali, Panu Mentula, Ari Leppäniemi and Ville Sallinen

The World Society of Emergency Surgery (WSES) spleen trauma classification: a useful tool in the management of splenic trauma

The World Society of Emergency Surgery (WSES) spleen trauma classification meets the need of an evolution of the current anatomical spleen injury scale considering both the anatomical lesions and their physiol...

Authors: Federico Coccolini, Paola Fugazzola, Lucia Morganti, Marco Ceresoli, Stefano Magnone, Giulia Montori, Matteo Tomasoni, Stefano Maccatrozzo, Niccolò Allievi, Savino Occhionorelli, Yoram Kluger, Massimo Sartelli, Gian Luca Baiocchi, Luca Ansaloni and Fausto Catena

Non-operative management of blunt hepatic and splenic injury: a time-trend and outcome analysis over a period of 17 years

A widespread shift to non-operative management (NOM) for blunt hepatic and splenic injuries has been observed in most centers worldwide. Furthermore, many countries introduced safety measures to systematically...

Authors: Margot Fodor, Florian Primavesi, Dagmar Morell-Hofert, Veronika Kranebitter, Anna Palaver, Eva Braunwarth, Matthias Haselbacher, Ulrich Nitsche, Stefan Schmid, Michael Blauth, Eva Gassner, Dietmar Öfner and Stefan Stättner

Hemostasis as soon as possible? The role of the time to angioembolization in the management of pelvic fracture

While transcatheter arterial embolization (TAE) is an effective way to control arterial bleeding associated with pelvic fracture, delayed TAE may increase mortality risk. The purpose of the current study was t...

Authors: Chang-Hua Chou, Yu-Tung Wu, Chih-Yuan Fu, Chien-Hung Liao, Shang-Yu Wang, Francesco Bajani and Chi-Hsun Hsieh

2019 WSES guidelines for the management of severe acute pancreatitis

Although most patients with acute pancreatitis have the mild form of the disease, about 20–30% develops a severe form, often associated with single or multiple organ dysfunction requiring intensive care. Ident...

Authors: Ari Leppäniemi, Matti Tolonen, Antonio Tarasconi, Helmut Segovia-Lohse, Emiliano Gamberini, Andrew W. Kirkpatrick, Chad G. Ball, Neil Parry, Massimo Sartelli, Daan Wolbrink, Harry van Goor, Gianluca Baiocchi, Luca Ansaloni, Walter Biffl, Federico Coccolini, Salomone Di Saverio…

Esophageal emergencies: WSES guidelines

The esophagus traverses three body compartments (neck, thorax, and abdomen) and is surrounded at each level by vital organs. Injuries to the esophagus may be classified as foreign body ingestion, caustic inges...

Authors: Mircea Chirica, Michael D. Kelly, Stefano Siboni, Alberto Aiolfi, Carlo Galdino Riva, Emanuele Asti, Davide Ferrari, Ari Leppäniemi, Richard P. G. ten Broek, Pierre Yves Brichon, Yoram Kluger, Gustavo Pereira Fraga, Gil Frey, Nelson Adami Andreollo, Federico Coccolini, Cristina Frattini…

REsiDENT 1 (Re-assessment of Appendicitis Evaluation during laparoscopic appendectomy: Do we End a Non-standardized Treatment approach and habit?): peritoneal irrigation during laparoscopic appendectomy—does the grade of contamination matter? A prospective multicenter resident-based evaluation of a new classification system

Laparoscopic appendectomy has progressively gained acceptance as the standard of care for acute appendicitis. Focusing on the incidence of postoperative intra-abdominal abscess after a laparoscopic appendectom...

Authors: Stefano Piero Bernardo Cioffi, Michele Altomare, Andrea Spota, Stefano Granieri, Stefania Cimbanassi and Osvaldo Chiara

Neutrophil heterogeneity and its role in infectious complications after severe trauma

Trauma leads to a complex inflammatory cascade that induces both immune activation and a refractory immune state in parallel. Although both components are deemed necessary for recovery, the balance is tight an...

Authors: Lillian Hesselink, Roy Spijkerman, Karlijn J. P. van Wessem, Leo Koenderman, Luke P. H. Leenen, Markus Huber-Lang and Falco Hietbrink

Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?

Approximately 20% of patients diagnosed with colorectal cancer will present with left-sided large bowel obstruction. The optimal management of this cohort of patients remains unclear. We aimed to review intern...

Authors: Peter John Webster, Joanna Aldoori and Dermot Anthony Burke

Educational value of surgical videos on YouTube: quality assessment of laparoscopic appendectomy videos by senior surgeons vs. novice trainees

To prepare for surgery, surgeons often recur to surgical videos, with YouTube being reported as the preferred source. This study aimed to compare the evaluation of three surgical trainees and three senior surg...

Authors: Nicola de’Angelis, Paschalis Gavriilidis, Aleix Martínez-Pérez, Pietro Genova, Margherita Notarnicola, Elisa Reitano, Niccolò Petrucciani, Solafah Abdalla, Riccardo Memeo, Francesco Brunetti, Maria Clotilde Carra, Salomone Di Saverio and Valerio Celentano

The intra-neuroendoscopic technique (INET): a modified minimally invasive technique for evacuation of brain parenchyma hematomas

Minimally invasive endoscopic hematoma evacuation is widely used in the treatment of intracerebral hemorrhage. However, this technique still has room for improvement. The intra-neuroendoscopic technique (INET)...

Authors: Yujuan Zhang, Ai-Jun Shan, Yu-Ping Peng, Pengfei Lei, Jianzhong Xu, Xianliang Zhong and Bo Du

Bowel obstruction: a narrative review for all physicians

Small and large bowel obstructions are responsible for approximately 15% of hospital admissions for acute abdominal pain in the USA and ~ 20% of cases needing acute surgical care. Starting from the analysis of...

Authors: Fausto Catena, Belinda De Simone, Federico Coccolini, Salomone Di Saverio, Massimo Sartelli and Luca Ansaloni

Damage control surgery for perforated diverticulitis with diffuse peritonitis: saves lives and reduces ostomy

Over the last decade, damage control surgery (DCS) has been emerging as a feasible alternative for the management of patients with abdominal infection and sepsis. So far, there is no consensus about the role o...

Authors: Dario Tartaglia, Gianluca Costa, Antonio Camillò, Maurizio Castriconi, Mauro Andreano, Michele Lanza, Pietro Fransvea, Paolo Ruscelli, Massimiliano Rimini, Christian Galatioto and Massimo Chiarugi

Melatonin treatment of pigs with acute pancreatitis reduces inflammatory reaction of pancreatic tissue and enhances fitness score of pigs: experimental research

Severe acute pancreatitis is associated with high morbidity and mortality. Melatonin is known as the activator of antioxidant enzymes. The main purpose of this study was to evaluate the clinical effect of mela...

Authors: Katharina Grupp, Johannes Erbes, Annika Poppe, Karin Wodack, Andreas Gocht, Constantin Trepte, Jan Havel, Oliver Mann, Jakob R. Izbicki and Kai Bachmann

Management of intrathoracic and cervical anastomotic leakage after esophagectomy for esophageal cancer: a systematic review

Anastomotic leakage (0–30%) after esophagectomy is a severe complication and is associated with considerable morbidity and mortality. The aim of this study was to determine which treatment for anastomotic leak...

Authors: Moniek H. P. Verstegen, Stefan A. W. Bouwense, Frans van Workum, Richard ten Broek, Peter D. Siersema, Maroeska Rovers and Camiel Rosman

Challenges faced by acute care surgeons in China

The aim of this article is to describe briefly about Chinese ACS surgeons’ work status. It is an undeniable fact that the analysis of ED and ACS resources shows negative tendencies and high work overload, resu...

Authors: Dequan Xu, Limin Hou and Haoxin Zhou

The role of the intra-abdominal view in complicated intra-abdominal infections

The prognostic role of what a surgeon observes in the abdomen of patients with complicated intra-abdominal infection (cIAI) is largely unknown. The aim of this prospective study was to systemically analyze com...

Authors: Matti Tolonen, Ville Sallinen, Ari Leppäniemi, Minna Bäcklund and Panu Mentula

Prediction of arterial extravasation in pelvic fracture patients with stable hemodynamics using coagulation biomarkers

Determining the presence of an active arterial hemorrhage in the acute phase is important as a treatment strategy in patients with pelvic fracture. The purpose of this study was to evaluate whether coagulation...

Authors: Makoto Aoki, Takayuki Ogura, Shuichi Hagiwara, Mitsunobu Nakamura and Kiyohiro Oshima

The impact of polytrauma on sRAGE levels: evidence and statistical analysis of temporal variations

According to recently published findings, levels of the soluble receptor of advanced glycation end products (sRAGE) and its clearance from the blood may reflect the evolution of lung damage during hospitalizat...

Authors: Lukas L. Negrin, Robin Ristl, Gabriel Halat, Thomas Heinz and Stefan Hajdu

Intra-operative gallbladder scoring predicts conversion of laparoscopic to open cholecystectomy: a WSES prospective collaborative study

Laparoscopic cholecystectomy, the gold-standard approach for cholecystectomy, has surprisingly variable outcomes and conversion rates. Only recently has operative grading been reported to define disease severi...

Authors: Michael Sugrue, Federico Coccolini, Magda Bucholc and Alison Johnston

Development and validation of a novel predictive score for sepsis risk among trauma patients

Patients suffering from major trauma often experience complications such as sepsis. The early recognition of patients at high risk of sepsis after trauma is critical for precision therapy. We aimed to derive a...

Authors: Hong-xiang Lu, Juan Du, Da-lin Wen, Jian-hui Sun, Min-jia Chen, An-qiang Zhang and Jian-xin Jiang

2017 WSES and SICG guidelines on acute calcolous cholecystitis in elderly population

Gallstone disease is very common afflicting 20 million people in the USA. In Europe, the overall incidence of gallstone disease is 18.8% in women and 9.5% in men. The frequency of gallstones related disease in...

Authors: Michele Pisano, Marco Ceresoli, Stefania Cimbanassi, Kurinchi Gurusamy, Federico Coccolini, Giuseppe Borzellino, Gianluca Costa, Niccolò Allievi, Bruno Amato, Djamila Boerma, Pietro Calcagno, Luca Campanati, Fabio Cesare Campanile, Alberto Casati, Osvaldo Chiara, Antonio Crucitti…

Preserve encephalus in surgery of trauma: online survey. (P.E.S.T.O)

Traumatic brain injury (TBI) is a global health problem. Extracranial hemorrhagic lesions needing emergency surgery adversely affect the outcome of TBI. We conducted an international survey regarding the acute...

Authors: Edoardo Picetti, Ronald V. Maier, Sandra Rossi, Andrew W. Kirkpatrick, Walter L. Biffl, Philip F. Stahel, Ernest E. Moore, Yoram Kluger, Gian Luca Baiocchi, Luca Ansaloni, Vanni Agnoletti and Fausto Catena

2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients

In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical pa...

Authors: Massimo Sartelli, Stefano Di Bella, Lynne V. McFarland, Sahil Khanna, Luis Furuya-Kanamori, Nadir Abuzeid, Fikri M. Abu-Zidan, Luca Ansaloni, Goran Augustin, Miklosh Bala, Offir Ben-Ishay, Walter L. Biffl, Stephen M. Brecher, Adrián Camacho-Ortiz, Miguel A. Caínzos, Shirley Chan…

Open conversion for laparoscopically difficult cholecystectomy is still a valid solution with unsolved aspects

The difficult laparoscopic cholecystectomy remains a surgical challenge for surgeons who must decide between laparoscopic continuation and open conversion. The balance between the lack of open surgery training...

Authors: M. Mannino, A. Toro, M. Teodoro, F. Coccolini, M. Sartelli, L. Ansaloni, F. Catena and I. Di Carlo

Pre-hospital plasma in haemorrhagic shock management: current opinion and meta-analysis of randomized trials

Trauma-induced coagulopathy is one of the most difficult issues to manage in severely injured patients. The plasma efficacy in treating haemorrhagic-shocked patients is well known. The debated issue is the tim...

Authors: Federico Coccolini, Giacinto Pizzilli, Davide Corbella, Massimo Sartelli, Vanni Agnoletti, Vanessa Agostini, Gian Luca Baiocchi, Luca Ansaloni and Fausto Catena

Medications and patient safety in the trauma setting: a systematic review

Medication errors account for the most common adverse events and a significant cause of mortality in the USA. The Joint Commission has required medication reconciliation since 2006. We aimed to survey the lite...

Authors: Jonathan H. DeAntonio, Tammy Nguyen, Gregory Chenault, Michel B. Aboutanos, Rahul J. Anand, Paula Ferrada, Stephanie Goldberg, Stefan W. Leichtle, Levi D. Procter, Edgar B. Rodas, Alan P. Rossi, James F. Whelan, V. Ramana Feeser, Michael J. Vitto, Beth Broering, Sarah Hobgood…

Feasibility of ultrasound measurement in a human model of acute compartment syndrome

Early diagnosis of acute compartment syndrome (ACS) of the leg is essential to improve the outcome. Direct invasive measurement is currently recommended to measure intracompartmental pressure. A non-invasive a...

Authors: Jakob Mühlbacher, Reinhard Pauzenberger, Ulrika Asenbaum, Tobias Gauster, Stephan Kapral, Harald Herkner and Andreas Duma

Transcatheter arterial embolization versus surgery for refractory non-variceal upper gastrointestinal bleeding: a meta-analysis

Nowadays, very few patients with non-variceal upper gastrointestinal bleeding fail endoscopic hemostasis (refractory NVUGIB). This subset of patients poses a clinical dilemma: should they be operated on or ref...

Authors: Antonio Tarasconi, Gian Luca Baiocchi, Vittoria Pattonieri, Gennaro Perrone, Hariscine Keng Abongwa, Sarah Molfino, Nazario Portolani, Massimo Sartelli, Salomone Di Saverio, Arianna Heyer, Luca Ansaloni, Federico Coccolini and Fausto Catena

Is early appendectomy in adults diagnosed with acute appendicitis mandatory? A prospective study

Prompt appendectomy has long been the standard of care for acute appendicitis in order to prevent complications such as perforation, abscess formation, and diffuse purulent or fecal peritonitis, all resulting ...

Authors: Salma Abu Foul, Ella Egozi, Ahmad Assalia, Yoram Kluger and Ahmad Mahajna

Kunafa knife and play dough is an efficient and cheap simulator to teach diagnostic Point-of-Care Ultrasound (POCUS)

Point-of-Care Ultrasound (POCUS) is a useful diagnostic tool. Nevertheless, it needs proper training to reach its required level of competency. Educators who work in low-income countries find it difficult to p...

Authors: Fikri M. Abu-Zidan and Arif Alper Cevik

2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to...

Authors: Massimo Sartelli, Xavier Guirao, Timothy C. Hardcastle, Yoram Kluger, Marja. A. Boermeester, Kemal Raşa, Luca Ansaloni, Federico Coccolini, Philippe Montravers, Fikri M. Abu-Zidan, Michele Bartoletti, Matteo Bassetti, Offir Ben-Ishay, Walter L. Biffl, Osvaldo Chiara, Massimo Chiarugi…

Predictors of Change in Functional Outcome at six months and twelve months after Severe Injury: A Retrospective Cohort Study

There is increasing focus on long-term survival, function and quality-of-life for trauma patients. There are few studies tracking longitudinal changes in functional outcome over time. The goal of our study was...

Authors: Aidan Lyanzhiang Tan, Yi Chiong, Nivedita Nadkarni, Jolene Yu Xuan Cheng, Ming Terk Chiu and Ting Hway Wong

First clinical experiences of concurrent bleeding control and intracranial pressure monitoring using a hybrid emergency room system in patients with multiple injuries

The outcomes of multiple injury patients with concomitant torso hemorrhage and traumatic brain injury (TBI) are very poor. The hybrid emergency room system (HERS) is a trauma management system designed to comp...

Authors: Takahiro Kinoshita, Kazuma Yamakawa, Jumpei Yoshimura, Atsushi Watanabe, Yosuke Matsumura, Kaori Ito, Hiroyuki Ohbe, Kei Hayashida, Shigeki Kushimoto, Junichi Matsumoto and Satoshi Fujimi

Outcomes of selective nonoperative management of civilian abdominal gunshot wounds: a systematic review and meta-analysis

Although mandatory laparotomy has been standard of care for patients with abdominal gunshot wounds (GSWs) for decades, this approach is associated with non-therapeutic operations, morbidity, and long hospital ...

Authors: Aziza N. Al Rawahi, Fatma A. Al Hinai, Jamie M. Boyd, Christopher J. Doig, Chad G. Ball, George C. Velmahos, Andrew W. Kirkpatrick, Pradeep H. Navsaria and Derek J. Roberts

Three cases of resuscitative endovascular balloon occlusion of the aorta (REBOA) in austere pre-hospital environment—technical and methodological aspects

The present paper describes three cases where ER-REBOA® was used with partial aorta occlusion (AO), by performing a partial resuscitative endovascular balloon occlusion of the aorta or pREBOA, in an austere pr...

Authors: J. C. de Schoutheete, I. Fourneau, F. Waroquier, L. De Cupere, M. O’Connor, K. Van Cleynenbreugel, J. C. Ceccaldi and S. Nijs

Vacuum-assisted closure (VAC®) systems and microbiological isolation of infected wounds

Negative pressure wound therapy is now largely used to treat infected wounds. The prevention and reduction of healthcare-associated infections is a high priority for any Department of Health and great efforts ...

Authors: Valerio Cozza, Gilda Pepe, Marco Cintoni, Flavio De Maio, Giuseppe Tropeano, Sabina Magalini, Gabriele Sganga, Giovanni Delogu and Daniele Gui

LBP rs2232618 polymorphism contributes to risk of sepsis after trauma

Previous study revealed that rs2232618 polymorphism (Phe436Leu) within LBP gene is a functional variant and associated with susceptibility of sepsis in traumatic patients. Our aim was to confirm the reported a...

Authors: Hong-xiang Lu, Jian-hui Sun, Da-lin Wen, Juan Du, Ling Zeng, An-qiang Zhang and Jian-xin Jiang

Multi-organ protection of ulinastatin in traumatic cardiac arrest model

Post-cardiac arrest syndrome, which has no specific curative treatment, contributes to the high mortality rate of victims who suffer traumatic cardiac arrest (TCA) and initially can be resuscitated. In the pre...

Authors: Shaoyun Liu, Jiefeng Xu, Yuzhi Gao, Peng Shen, Senlin Xia, Zilong Li and Mao Zhang

Abdominopelvic trauma: from anatomical to anatomo-physiological classification

Abdominopelvic trauma has been for decades classified with the AAST-OIS (American Association for the Surgery of Trauma—Organ Injury Scale) classification. It has represented a milestone. At present, the medic...

Authors: Federico Coccolini, Fausto Catena, Yoram Kluger, Massimo Sartelli, Gianluca Baiocchi, Luca Ansaloni and Ernest Eugene Moore

Effect of resuscitative endovascular balloon occlusion of the aorta in hemodynamically unstable patients with multiple severe torso trauma: a retrospective study

Although resuscitative endovascular balloon occlusion of the aorta (REBOA) may be effective in trauma management, its effect in patients with severe multiple torso trauma remains unclear.

Authors: Hiroyuki Otsuka, Toshiki Sato, Keiji Sakurai, Hiromichi Aoki, Takeshi Yamagiwa, Shinichi Iizuka and Sadaki Inokuchi

Small bowel obstruction in the elderly: a plea for comprehensive acute geriatric care

Small bowel obstruction is one of the most frequent emergencies in general surgery, commonly affecting elderly patients. Morbidity and mortality from small bowel obstruction in elderly is high. Significant pro...

Authors: Ekin Ozturk, Marianne van Iersel, Martijn MWJ Stommel, Yvonne Schoon, Richard RPG ten Broek and Harry van Goor

Diagnostic point-of-care ultrasound (POCUS) for gastrointestinal pathology: state of the art from basics to advanced

The use of point-of-care ultrasound (POCUS) by non-radiologists has dramatically increased. POCUS is completely different from the routine radiological studies. POCUS is a Physiological, On spot, extension of ...

Authors: Fikri M Abu-Zidan and Arif Alper Cevik

A tribute to Ernest E. “Gene” Moore

Authors: Jeffry Kashuk, Walter Biffl, Yoram Kluger, Luca Ansaloni and Fausto Catena