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Table 3 Predictors of complications according to univariate and multivariate logistic regression analysis

From: Clinical profile and outcome of surgical treatment of perforated peptic ulcers in Northwestern Tanzania: A tertiary hospital experience

Predictor(independent) variable Complication N (%) No complication n (%) Univariate analysis Multivariate analysis
    O.R. 95% C.I. p-value O.R. 95% C.I. p-value
Age (in years)       
<40 15 (28.8) 37 (71.2)     
≥40 10 (31.2) 22 (68.8) 3.91(0.94-5.23) 0.167 1.23(0.93-2.34) 0.786
Sex       
Male 14 (29.2) 36 (70.8)     
Female 11 (30.6) 25 (69.4) 1.87(0.22-4.88) 0.334 3.32(0.45-4.66) 0.937
Premorbid illness       
Yes 4 (66.7) 2(33.3)     
No 21(26.9) 57(73.1) 3.54(1.33-5.87) 0.012 5.28(2.39-6.82) 0.007
Previous PUD       
Yes 7(26.9) 19(73.1)     
No 18(31.0) 40(69.0) 0.21(0.11-1.78) 0.051 1.65(0.32-2.89) 0.786
NSAIDs use       
Yes 3(33.3) 6(66.7)     
No 22(29.3) 53(70.7) 1.98(0.99-3.91) 0.923 1.02(0.78-3.90) 0.123
Alcohol use       
Yes 22(30.6) 50(69.4)     
No 3(25.0) 9(75.0) 3.05(0.19-2.86) 0.054 0.45(0.22-5.21) 0.321
Cigarette smoking       
Yes 17(31.5) 37(68.5)     
No 8(26.7) 22(73.3) 3.11(0.44-5.23) 0.145 3.02(0.99-4.56) 0.334
Treatment delay       
< 48 18(90.0) 2(10.0)     
≥ 48 7(14.6) 41(85.4) 1.06(1.01-5.45) 0.021 0.23(0.11-0.95) 0.003
HIV status       
Positive 6(75.0) 2 (25.0)     
Negative 19(25.0) 57(75.0) 2.87(1.22-4.97) 0.023 1.92(1.31-4.22 0.001
CD4 count       
< 200 cells/μl 1 (50.0) 1(50.0)     
≥ 200 cells/μl 1(16.7) 5(83.3) 4.05(3.27-5.01) 0.029 2,94(2.44-6.98) 0.000
Nature of perforation       
Acute 24(32.4) 50(67.6)     
Chronic 1(10.0) 9(90.0) 4.94(2.84-8.92) 0.009 2.95(1.11-6.98) 0.018