Table 3 Predictors of complications according to univariate and multivariate logistic regression analysis

Age (in years)

<40

15 (28.8)

37 (71.2)

≥40

10 (31.2)

22 (68.8)

3.91(0.94-5.23)

0.167

1.23(0.93-2.34)

0.786

Sex

Male

14 (29.2)

36 (70.8)

Female

11 (30.6)

25 (69.4)

1.87(0.22-4.88)

0.334

3.32(0.45-4.66)

0.937

Premorbid illness

Yes

4 (66.7)

2(33.3)

No

21(26.9)

57(73.1)

3.54(1.33-5.87)

0.012

5.28(2.39-6.82)

0.007

Previous PUD

Yes

7(26.9)

19(73.1)

No

18(31.0)

40(69.0)

0.21(0.11-1.78)

0.051

1.65(0.32-2.89)

0.786

NSAIDs use

Yes

3(33.3)

6(66.7)

No

22(29.3)

53(70.7)

1.98(0.99-3.91)

0.923

1.02(0.78-3.90)

0.123

Alcohol use

Yes

22(30.6)

50(69.4)

No

3(25.0)

9(75.0)

3.05(0.19-2.86)

0.054

0.45(0.22-5.21)

0.321

Cigarette smoking

Yes

17(31.5)

37(68.5)

No

8(26.7)

22(73.3)

3.11(0.44-5.23)

0.145

3.02(0.99-4.56)

0.334

Treatment delay

< 48

18(90.0)

2(10.0)

≥ 48

7(14.6)

41(85.4)

1.06(1.01-5.45)

0.021

0.23(0.11-0.95)

0.003

HIV status

Positive

6(75.0)

2 (25.0)

Negative

19(25.0)

57(75.0)

2.87(1.22-4.97)

0.023

1.92(1.31-4.22

0.001

CD4 count

< 200 cells/μl

1 (50.0)

1(50.0)

≥ 200 cells/μl

1(16.7)

5(83.3)

4.05(3.27-5.01)

0.029

2,94(2.44-6.98)

0.000

Nature of perforation

Acute

24(32.4)

50(67.6)

Chronic

1(10.0)

9(90.0)

4.94(2.84-8.92)

0.009

2.95(1.11-6.98)

0.018