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Table 3 Performance characteristics estimate of normal versus different groups

From: Clinical value of total white blood cells and neutrophil counts in patients with suspected appendicitis: retrospective study

Parameters

Cutoff point

Sensitivity

Specificity

PPV

NPV

LR(+)

LR(−)

normal versus all abnormal appendix ( n = 456)

WBCs count 95% CIs

9.400 X103

76.81 (72.5 - 80.7)

65.52 (45.7 - 82.1)

97.0 (4.6 - 98.6)

16.1 (10.0 - 24.0)

2.23 (1.7- 2.9)

0.35 (0.2 - 0.6)

Neutrophil count 95% Cls

7.540X103

70.96 (66.4 - 75.2)

65.52 (45.7 - 82.1)

96.8 (94.2 - 98.5)

13.3 (8.2 - 20.0)

2.06 (1.6 - 2.7)

0.44 (0.3 - 0.7)

normal versus inflamed appendix ( n = 379)

WBCs count 95% CIs

9.400 X103

75.43 (70.6 - 79.8)

65.52 (45.7 - 82.1)

96.4 (93.4 - 98.2)

18.1 (11.2 - 26.9)

2.19 (1.7 - 2.9)

0.38 (0.2 - 0.6)

Neutrophil count 95% Cls

8.080X103

65.43 (60.2 - 70.4)

68.97 (49.2 - 84.7)

96.2 (92.9 - 98.3)

14.2 (8.9 - 21.1)

2.11 (1.6 - 2.7)

0.50 (0.3 - 0.9)

normal versus complicated appendix ( n = 106)

WBCs count 95% CIs

11.100 X103

76.62 (65.6 - 85.5)

72.41 (52.8 - 87.3)

88.10 (77.8 - 94.7)

53.80 (37.2 - 69.9)

2.78 (2.1 - 3.6)

0.32 (0.2 - 0.7)

Neutrophil count 95% Cls

7.540X103

81.82 (71.4 - 89.7)

65.52 (45.7 - 82.1)

86.30 (76.2 - 93.2)

57.60 (38.9 - 74.8)

2.37 (1.8 - 3.2)

0.28 (0.1 - 0.6)

  1. WBCs white blood cells, 95% CIs 95% confidence intervals, NPV negative predictive value, PPV positive predictive value, LR likelihood ratio.