Damage control operations in non-trauma patients: defining criteria for the staged rapid source control laparotomy in emergency general surgery

Table 5 Logistic regression analyses predicting in-hospital mortality for RSCL patients

Variable^a	Unadjusted model^a		Adjusted multivariable model^b
Variable^a	OR (95 % CI)	p-value^c	OR (95 % CI)	p-value^c
Preoperative inflammatory status:
No inflammation	1.26 (0.32–5.01)	0.7397	1.00	-
Sepsis	0.44 (0.15–1.32)	0.1415	0.60 (0.07–5.39)	0.6446
Severe sepsis/septic shock	2.30 (0.68–7.80)	0.1811	3.29 (0.26–41.92)	0.3596
Patient Characteristics:
Male Gender	0.96 (0.32–2.85)	0.9416	0.55 (0.07–4.28)	0.5708
Race, White	0.58 (0.12–2.88)	0.5022	0.26 (0.01–8.47)	0.4509
Age (≥70)	1.59 (0.51–4.92)	0.4230	5.19 (0.75–35.74)	0.0942
No comorbidities	1.20 (0.40–3.57)	0.7448	1.00	-
1 comorbidity	1.22 (0.07–20.55)	0.8915	999 (0.001–999.99)	0.9848
2 comorbidities	0.89 (0.18–4.45)	0.8900	0.58 (0.05–6.08)	0.6458
≥3 comorbidities	0.85 (0.28–2.58)	0.7739	0.06 (0.01–0.70)	0.0252
Preoperative metrics:
Acidosis (pH ≤ 7.25)	1.92 (0.60–6.15)	0.2703	19.42 (1.74–216.65)	0.0159
Lactate (≥3)	0.79 (0.26–2.40)	0.6831	0.10 (0.01–0.93)	0.0431
Coagulopathy (INR ≥ 1.7)	1.53 (0.36–6.55)	0.5680	2.14 (0.27–16.83)	0.4682
ASA score, 1 or 2	-	-	1.00	-
ASA score, 3	0.14 (0.02–1.20)	0.0729	1.00	-
ASA score, 4 or 5	7.32 (0.83–64.43)	0.0729	26.45 (0.82–857.50)	0.0650

RSCL rapid source control laparotomy, PRBC packed red blood cells, C Celsius, INR international normalized ratio, ASA American Society of Anesthesiologists
^aUnadjusted univariate analyses were used to test an independent variables’s predictive ability on in-hospital mortality
^bModel covariates for mortality were chosen by full selection
^c P-value of <0.05 significant

ISSN: 1749-7922