Table 1 Distribution of clinical predictive variables of in-hospital mortality
From: Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study
Variables | Total patients | Dead | Survivors | RR | p value |
|---|---|---|---|---|---|
n 3137 | n 280 | n 2857 | |||
(100%) | (8.9%) | (91.1%) | |||
Age > 80 years | 246 (7.8) | 72 (25.7) | 174 (6.1) | 4.07 (3.22–5.14) | < 0.001 |
Immunodeficiency | 240 (7.7) | 56 (20.0) | 184 (6.4) | 3.02 (2.32–3.92) | < 0.001 |
Malignancy | 333 (10.6) | 83 (29.6) | 250 (8.8) | 3.55 (2.82–4.46) | < 0.001 |
Severe cardiovascular disease | 406 (12.9) | 106 (37.9) | 300 (10.5) | 4.10 (3.30–5.10) | < 0.001 |
Diabetes | 400 (12.8) | 76 (27.1) | 324 (11.3) | 2.55 (2.00–3.25) | < 0.001 |
Severe CKD | 141 (4.5) | 52 (18.6) | 89 (3.1) | 4.85 (3.78–6.22) | < 0.001 |
Severe COPD | 186 (5.9) | 60 (21.4) | 126 (4.4) | 4.33 (3.39–5.52) | < 0.001 |
Core temperature (°C) | |||||
< 36.0 | 85 (2.7) | 23 (8.2) | 62 (2.2) | 3.21 (2.22–4.64) | < 0.001 |
36.0–38.0 | 2292 (73.1) | 185 (66.1) | 2107 (73.7) | 0.72 (0.57–0.91) | < 0.05 |
> 38.0 | 760 (24.2) | 72 (25.7) | 688 (24.1) | 1.08 (0.84–1.40) | 0.54 |
Hearth rate (bpm) | |||||
< 60 | 8 (0.3) | 1 (0.4) | 7 (0.2) | 1.40 (0.22–8.80) | 0.72 |
60–100 | 1919 (61.2) | 117 (41.8) | 1802 (63.1) | 0.46 (0.36–0.57) | < 0.001 |
> 100 | 1210 (38.6) | 162 (57.9) | 1048 (36.7) | 2.19 (1.74–2.74) | < 0.001 |
Systolic blood pressure (mmHg) | |||||
< 90 | 138 (4.4) | 49 (17.5) | 89 (3.1) | 4.61 (3.57–5.96) | < 0.001 |
90–100 | 388 (12.4) | 70 (25.0) | 318 (11.1) | 2.36 (1.84–3.03) | < 0.001 |
> 100 | 2610 (83.2) | 161 (57.5) | 2449 (85.7) | 0.27 (0.22–0.34) | < 0.001 |
Respiratory rate (breaths/min) | |||||
< 22 | 2244 (71.5) | 124 (44.3) | 2120 (74.2) | 0.32 (0.25–0.40) | < 0.001 |
22–29 | 684 (21.8) | 97 (34.6) | 587 (20.5) | 1.90 (1.50–2.39) | < 0.001 |
30–35 | 154 (4.9) | 39 (13.9) | 115 (4.0) | 3.13 (2.33–4.21) | < 0.001 |
> 35 | 55 (1.8) | 20 (7.1) | 35 (1.2) | 4.31 (2.98–6.23) | < 0.001 |
AVPU responsiveness scale | |||||
Alert | 2917 (93.0) | 187 (66.8) | 2730 (95.6) | 0.15 (0.12–0.19) | < 0.001 |
Voice | 123 (3.9) | 54 (19.3) | 69 (2.4) | 5.85 (4.62–7.41) | < 0.001 |
Pain | 74 (2.4) | 23 (8.2) | 51 (1.8) | 3.70 (2.59–5.30) | < 0.001 |
Unresponsive | 23 (0.7) | 16 (5.7) | 7 (0.2) | 8.21 (6.12–11.01) | < 0.001 |
NRS | |||||
0–3 | 80 (2.6) | 16 (5.7) | 64 (2.2) | 2.32 (1.47–3.64) | < 0.001 |
4–6 | 1512 (48.2) | 112 (40.0) | 1400 (49.0) | 0.72 (0.57–0.90) | < 0.05 |
7–10 | 1112 (35.4) | 128 (45.7) | 984 (34.4) | 1.53 (1.23–1.92) | < 0.001 |
Not reported | 433 (13.8) | 24 (8.6) | 409 (14.3) | NA | NA |
qSOFA score | |||||
0 | 1367 (43.6) | 37 (13.2) | 1330 (46.6) | 0.20 (0.14–0.28) | < 0.001 |
1 | 1323 (42.2) | 109 (38.9) | 1214 (42.5) | 0.87 (0.96–1.10) | 0.25 |
2 | 353 (11.3) | 84 (30.0) | 269 (9.4) | 3.38 (2.68–4.26) | < 0.001 |
3 | 94 (3.0) | 50 (17.9) | 44 (1.5) | 7.04 (5.61–8.82) | < 0.001 |