Association of pre-operative chronic kidney disease and acute kidney injury with in-hospital outcomes of emergency colorectal surgery: a cohort study

Table 2 In-hospital outcomes of study participants with emergency colorectal surgery

	Total n = 3002	CKD(-)AKI(-) n = 1963	CKD(-)AKI(+) n = 541	CKD(+)AKI(-) n = 340	CKD(+)AKI(+) n = 59	ESRD n = 99	P value
Primary outcome
In-hospital mortality, %	13.3	8.6	23.8	15.3	28.8	32.3	< 0.001
Secondary outcomes
Use of mechanical ventilation on the next day of surgery or later, %	26.9	21.1	43.8	24.7	44.1	46.5	< 0.001
Use of mechanical ventilation on the next day of surgery or later, %	6.5	4.0	10.7	8.2	15.3	21.2	< 0.001
Blood transfusion during hospitalization, %	38.6	30.2	56.8	46.8	55.9	68.7	< 0.001
Red cell concentrate, %	35.1	27.3	51.2	43.2	52.5	63.6	< 0.001
Platelet concentrate, %	4.7	3.0	8.3	4.1	10.2	16.2	< 0.001
Fresh-frozen plasma, %	24.3	18.0	41.0	25.0	39.0	45.5	< 0.001
Post-operative RRT, %	9.6	4.0	11.3	10.6	28.8	96.0	< 0.001
Continuous RRT, %	7.3	3.8	10.4	8.5	22.0	46.5	< 0.001
Intermittent RRT, %	4.2	0.4	2.0	2.9	11.9	90.9	< 0.001
Length of hospital stay in hospital survivors (days), median [IQR]	23 [14–40]	21 [13–35]	33 [20–55]	27 [16–42]	37 [18–58]	34 [24–69]	< 0.001

AKI acute kidney injury, CKD chronic kidney disease, ESRD end-stage renal disease, IQR interquartile range, RRT renal replacement therapy

ISSN: 1749-7922