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Table 1 Demographic and clinical data of patient cohorts and adult controls

From: Trauma induced clotting factor depletion in severely injured children: a single center observational study

 

SI

MI

CO

 

Demographics

Mean, median, or %

SD/IQR

Mean, median, or %

SD/IQR

p*

Mean, median, or %

SD/IQR

p*

Age, year

9

6

11

5

0.30

40

9

< 0.001

Sex (male)

75.0%

 

62.5%

 

1.00

70,0%

 

1.00

Isolated TBI

12.5%

 

25.0%

 

1.00

   

Survival

87.5%

 

100%

 

1.00

   

ISS

25

19-28

5

4-6

< 0.001

   

INR

1.21

1.04-1.58

1.07

1.04-1.09

0.13

0.96

0.93-1.00

0.001

PTT (sec)

26.7

24.1-34.6

26.0

25.0-28.5

0.88

28.8

26.6-31.0

0.57

Hemoglobin (g/dl)

11.8

9.9-12.6

12.9

11.5-13.6

0.11

14.9

13.8-15.6

n/a

Thrombocytes/nl

279

179-311

273

209-307

1.00

226

183-298

n/a

  1. The demographic and clinical data of severely injured children (SI, n = 8) were compared with those of children with minor injury (MI, n = 8) and an adult control group (CO, n = 10). Age is given as mean value with standard deviation (SD) whereas male sex, isolated traumatic brain injury (TBI), and survival rate are demonstrated as percentages. All other variables represent median values together with interquartile range (IQR, 25th to 75th percentile)
  2. n/a not applicable
  3. *Independent-samples t test (age), Fisher’s Exact test (sex, isolated TBI, survival), and Mann-Whitney U test versus SI