Impact of fibrinogen level on the prognosis of patients with traumatic brain injury: a single-center analysis of 2570 patients

Table 3 Correlation between fibrinogen levels and mortality

Predictors	OR (95% CI)	P value^a
3-month mortality for patients with fibrinogen level < 2.0 g/L
Age	1.035 (1.019–1.051)	< .001
GCS	0.811 (0.739–0.891)	< .001
Pupillary reactions	2.240 (1.467–3.421)	< .001
EDH	0.280 (0.149–0.526)	< .001
INR	4.316 (1.556–11.975)	.005
FIB	0.522 (0.273–0.995)	.048
3-month mortality for patients with fibrinogen level < 2.0 g/L vs. ≥ 2.0 g/L groups
AGE	1.035 (1.024–1.047)	< .001
GCS	0.760 (0.716–0.807)	< .001
Pupillary reactions	1.874 (1.404–2.500)	< .001
EDH	0.399 (0.253–0.630)	< .001
PT	1.215 (1.125–1.312)	< .001
FIBG^b	0.622 (0.439–0.882)	.008

GCS Glasgow Coma Scale, INR international normalized ratio, PT prothrombin, FIB fibrinogen, EDH epidural hematoma, SDH subdural hematoma
^aP values adjusted for multiple comparisons. Statistical significance determined by multiple logistic regression analysis
^bFIBG means patients with fibrinogen level < 2.0 g/L or ≥ 2.0 g/L groups

ISSN: 1749-7922