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Table 2 Characteristics of the propensity score-matched patients

From: Early administration of fibrinogen concentrate is associated with improved survival among severe trauma patients: a single-centre propensity score-matched analysis

 

Control group

n = 31

FC group

n = 31

Matched standardised difference

p value

Age (years)

55 (36–72)

53 (32–74)

− 0.006

0.978

Gender, male

25 (80.6)

19 (61.3)

− 0.435

0.093

Blunt trauma

29 (93.5%)

29 (93.5%)

< 0.001

1.000

Mechanism of the injury

 Traffic accident (in the car)

12 (38.7%)

12 (38.7%)

< 0.001

1.000

 Traffic accident (pedestrian)

11 (35.5%)

11 (35.5%)

< 0.001

 Fall

6 19.4%)

6 19.4%)

< 0.001

 Invert

0 (0.0%)

0 (0.0%)

< 0.001

 Stab wound/cutting

2 (6.5%)

2 (6.5%)

< 0.001

 Others

0 (0.0%)

0 (0.0%)

< 0.001

Injury to the admission to the ED

 0–30 (min)

6 (19.3%)

6 (19.3%)

< 0.001

0.963

 30–60 (min)

18 (58.0%)

18 (58.0%)

< 0.001

 60–90 (min)

4 (12.9%)

3 (9.67%)

− 0.102

 90– (min)

3 (9.67%)

4 (12.9%)

0.102

Revised trauma score

5.03 (4.09–6.90)

5.68 (4.45–6.38)

0.086

0.750

Probability of survival

0.684 (0.276–0.878)

0.724 (0.275–0.886)

0.043

0.894

Vital signs on the admission to ED

 Heart rate (per min)

94 (68–120)

105 (80–120)

0.119

0.578

 Glasgow coma scale

6 (3–13)

7 (4–14)

0.271

0.228

 Systolic Blood Pressure (mmHg)

112 (91–150)

100 (70–140)

− 0.135

0.383

 Respiratory rate (per min)

19 (16–24)

24 (16–30)

0.459

0.105

Injury severity score

30 (21–36)

34 (25–41)

0.353

0.182

 AIS head and neck

4 (0–5)

4 (0–5)

0.016

0.895

 AIS face

0 (0–0)

0 (0–1)

− 0.403

0.414

 AIS chest

3 (0–4)

3 (0–4)

− 0.164

0.699

 AIS abdomen

0 (0–2)

0 (0–3)

0.660

0.087

 AIS extremity

1 (0–3)

2 (0–3)

− 0.295

0.668

 AIS external

1 (0–1)

1 (0–1)

0.419

0.678

Blood gas analysis

 pH

7.33 (7.24−7.37)

7.25 (7.15−7.35)

− 0.283

0.095

 Base deficit (mmol/L)

3.7 (2.1− 6.7 )

6.3 (2.4–12.5)

− 0.343

0.130

 Lactate (mmol/L)

4.1 (2.9–5.5)

4.9 (3.0–7.9)

0.219

0.260

Laboratory data

 Platelet (× 103/μL)

208 (163–240)

193 (114–235)

− 0.158

0.559

 PT-INR

1.08 (1.03–1.27)

1.20 (1.10–1.40)

− 0.158

0.078

 Fibrinogen (mg/dL)

169 (124–200)

164 (138–219)

0.113

0.647

 FDP (μg/mL)

120.0 (66.6–267.0)

93.5 (43.0–188.0)

0.082

0.391

 D-dimer (μg/mL)

67.5 (46.5–207.7)

56.9 (20.4–125.0)

− 0.019

0.240

  1. FC fibrinogen concentrate, ED emergency department, AIS Abbreviated Injury Scale, PT-INR prothrombin time-international normalised ratio, FDP fibrin/fibrinogen degradation products