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Table 1 Characteristics of patients with acute appendicitis (N = 402)

From: Periappendiceal fat-stranding models for discriminating between complicated and uncomplicated acute appendicitis: a diagnostic and validation study

 

Uncomplicated appendicitis (N = 338)

Complicated appendicitis (N = 64)

P value

Demographic factors

   

 Age (years)

42.5 ± 16.5

49.0 ± 20.0

0.0170*

 Age groups (years)

  

0.0109*

  20–25

53 (15.7%)

8 (12.5%)

 

  26–35

90 (26.6%)

13 (20.3%)

 

  36–45

69 (20.4%)

14 (21.9%)

 

  46–55

47 (13.9%)

3 (4.7%)

 

  56–65

39 (11.5%)

8 (12.5%)

 

  ≥ 66

40 (11.8%)

18 (28.1%)

 

 Female (n/total n, %)

166 (49.1%)

35 (54.7%)

0.4134

 BMI

23.5 ± 3.9

24.3 ± 4.1

0.1814

Clinical findings in ED

   

 Duration of RLQ pain (days)

1.6 ± 1.0

2.5 ± 1.6

< 0.0001*

 Pain score (VAS)

5.4 ± 1.08

5.4 ± 1.9

0.9953

 Previous abdominal surgery

53 (15.7%)

5 (78.8%)

0.1005

 Duration of stay in ED (hour)

22.2 ± 11.1

21.4 ± 9.8

0.5706

 Body temperature (°C)

36.8 ± 0.6

37.2 ± 0.8

0.0008*

 Blood pressure

   

  Systolic

128.4 ± 19.1

129.7 ± 18.9

0.6217

  Diastolic

77.1 ± 14.5

77.8 ± 12.5

0.7467

  Mean arterial

94.2 ± 14.6

95.1 ± 13.6

0.6684

Laboratory factors in ED

   

 WBC count (103 cells/μL)

13.7 ± 4.1

14.6 ± 4.4

0.1420

 Neutrophil count (103 cells/μL)

11.1 ± 4.0

12.2 ± 4.1

0.0593

 Lymphocyte count (103 cells/μL)

1.6 ± 0.7

1.3 ± 0.7

0.0025

 NLR

8.9 ± 7.7

13.8 ± 0.7

< 0.0001*

 Platelet (103 cells/μL)

233.0 ± 54.4

240.5 ± 89.9

0.5181

 CRP level (mg/dL)

2.9 ± 4.2

12.8 ± 11.3

< 0.0001*

Radiological findings of CT in ED

   

 Appendicolith (N)

94 (27.9%)

31 (48.4%)

0.0011*

 Appendiceal diameter (cm)

10.96 ± 3.34

11.79 ± 4.24

0.1581

 Cecum wall thickness (cm)

0.04 ± 0.19

0.10 ± 0.31

0.0865

 Ascites (N)

46 (13.6%)

19 (29.7%)

0.0014*

 Appendiceal hyperemia (N)

213 (63.0%)

41 (64.1%)

0.8737

 Periappendiceal fluid (N)

38 (11.2%)

23 (35.9%)

< 0.0001*

 Intraluminal air (N)

43 (12.7%)

15 (23.4%)

0.0253*

 Extraluminal air (N)

1 (0.3%)

4 (6.3%)

0.0026*

 Fat stranding (N)

213(63.0%)

61 (95.3%)

< 0.0001*

 Fat stranding grades

1.0 ± 1.0

2.2 ± 0.9

< 0.0001*

 Fat stranding grades classification

  

< 0.0001*

  Grade 0

121 (35.8%)

3 (4.7%)

 

  Grade 1

111 (32.8%)

11 (17.2%)

 

  Grade 2

80 (23.7%)

22 (34.4%)

 

  Grade 3

26 (7.7%)

28 (43.8%)

 

Pathological findings

   

 Appendiceal length (cm)

5.45 ± 1.63

5.22 ± 1.49

0.3059

 Appendiceal width (cm)

0.95 ± 0.40

1.37 ± 0.78

< 0.0001*

 Infiltration (N)

83 (24.6%)

20 (31.3%)

0.2607

 Gangrenous (N)

0 (0%)

11 (17.2%)

< 0.0001*

 Perforatation (N)

0 (0%)

27 (42.2%)

< 0.0001*

Hospitalized days (day)

2.5 ± 1.3

5.4 ± 3.8

< 0.0001*

  1. BMI body mass index, cm centimeter, CRP C-reactive protein, CT computed tomography, ED emergency department, NLR neutrophil to lymphocyte ratio, RLQ right lower quadrant, VAS visual analog scale, WBC white blood cell
  2. *Statistical significance (P < 0.05)