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Table 1 Characteristics of patients with acute appendicitis (N = 402)

From: Periappendiceal fat-stranding models for discriminating between complicated and uncomplicated acute appendicitis: a diagnostic and validation study

  Uncomplicated appendicitis (N = 338) Complicated appendicitis (N = 64) P value
Demographic factors    
 Age (years) 42.5 ± 16.5 49.0 ± 20.0 0.0170*
 Age groups (years)    0.0109*
  20–25 53 (15.7%) 8 (12.5%)  
  26–35 90 (26.6%) 13 (20.3%)  
  36–45 69 (20.4%) 14 (21.9%)  
  46–55 47 (13.9%) 3 (4.7%)  
  56–65 39 (11.5%) 8 (12.5%)  
  ≥ 66 40 (11.8%) 18 (28.1%)  
 Female (n/total n, %) 166 (49.1%) 35 (54.7%) 0.4134
 BMI 23.5 ± 3.9 24.3 ± 4.1 0.1814
Clinical findings in ED    
 Duration of RLQ pain (days) 1.6 ± 1.0 2.5 ± 1.6 < 0.0001*
 Pain score (VAS) 5.4 ± 1.08 5.4 ± 1.9 0.9953
 Previous abdominal surgery 53 (15.7%) 5 (78.8%) 0.1005
 Duration of stay in ED (hour) 22.2 ± 11.1 21.4 ± 9.8 0.5706
 Body temperature (°C) 36.8 ± 0.6 37.2 ± 0.8 0.0008*
 Blood pressure    
  Systolic 128.4 ± 19.1 129.7 ± 18.9 0.6217
  Diastolic 77.1 ± 14.5 77.8 ± 12.5 0.7467
  Mean arterial 94.2 ± 14.6 95.1 ± 13.6 0.6684
Laboratory factors in ED    
 WBC count (103 cells/μL) 13.7 ± 4.1 14.6 ± 4.4 0.1420
 Neutrophil count (103 cells/μL) 11.1 ± 4.0 12.2 ± 4.1 0.0593
 Lymphocyte count (103 cells/μL) 1.6 ± 0.7 1.3 ± 0.7 0.0025
 NLR 8.9 ± 7.7 13.8 ± 0.7 < 0.0001*
 Platelet (103 cells/μL) 233.0 ± 54.4 240.5 ± 89.9 0.5181
 CRP level (mg/dL) 2.9 ± 4.2 12.8 ± 11.3 < 0.0001*
Radiological findings of CT in ED    
 Appendicolith (N) 94 (27.9%) 31 (48.4%) 0.0011*
 Appendiceal diameter (cm) 10.96 ± 3.34 11.79 ± 4.24 0.1581
 Cecum wall thickness (cm) 0.04 ± 0.19 0.10 ± 0.31 0.0865
 Ascites (N) 46 (13.6%) 19 (29.7%) 0.0014*
 Appendiceal hyperemia (N) 213 (63.0%) 41 (64.1%) 0.8737
 Periappendiceal fluid (N) 38 (11.2%) 23 (35.9%) < 0.0001*
 Intraluminal air (N) 43 (12.7%) 15 (23.4%) 0.0253*
 Extraluminal air (N) 1 (0.3%) 4 (6.3%) 0.0026*
 Fat stranding (N) 213(63.0%) 61 (95.3%) < 0.0001*
 Fat stranding grades 1.0 ± 1.0 2.2 ± 0.9 < 0.0001*
 Fat stranding grades classification    < 0.0001*
  Grade 0 121 (35.8%) 3 (4.7%)  
  Grade 1 111 (32.8%) 11 (17.2%)  
  Grade 2 80 (23.7%) 22 (34.4%)  
  Grade 3 26 (7.7%) 28 (43.8%)  
Pathological findings    
 Appendiceal length (cm) 5.45 ± 1.63 5.22 ± 1.49 0.3059
 Appendiceal width (cm) 0.95 ± 0.40 1.37 ± 0.78 < 0.0001*
 Infiltration (N) 83 (24.6%) 20 (31.3%) 0.2607
 Gangrenous (N) 0 (0%) 11 (17.2%) < 0.0001*
 Perforatation (N) 0 (0%) 27 (42.2%) < 0.0001*
Hospitalized days (day) 2.5 ± 1.3 5.4 ± 3.8 < 0.0001*
  1. BMI body mass index, cm centimeter, CRP C-reactive protein, CT computed tomography, ED emergency department, NLR neutrophil to lymphocyte ratio, RLQ right lower quadrant, VAS visual analog scale, WBC white blood cell
  2. *Statistical significance (P < 0.05)